Hanieh-Sadat Ejtahed
Obesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
[ 1 ] - Congenital Generalized Lipodystrophy in a Youth Presented with Sclerotic and Lytic Bone Lesions; a Family with AGPAT2 Mutation
BackgroundCongenital generalized lipodystrophy (CGL) is a rare disease. It is associated with near total fat loss, severe insulin resistance and hypoleptinemia leading to metabolic derangements.Case PresentationWe report a 25- year- old female with 1-Acylglycerol-3-phosphate-O-acyltransferase 2 (APGAT2) mutation, and both sclerotic and lytic bone lesions together for the first time. Bone cyst i...
[ 2 ] - اثر دریافت مکمل پروبیوتیک بر سطوح گلوکز، مقاومت انسولینی و شاخصهای التهابی در بیماران مبتلا به دیابت نوع دو: کارآزمایی بالینی شاهددار تصادفی شده
مقدمه: التهاب سیستمیک در بروز عوارض ناشی از دیابت نقش عمده‌ای را برعهده دارد. پروبیوتیکها به دلیل دارا بودن اثرات ضد التهابی می‌توانند در درمان عوارض ناشی از دیابت مورد استفاده قرار گیرند. مطالعه‌ی حاضر با هدف بررسی تاثیر مصرف مکمل پروبیوتیک بر روی سطوح گلوکز خون، مقاومت انسولینی و شاخصهای التهابی در بیماران مبتلا به دیابت نوع 2 انجام شد. مواد و روشها: این کارآزمایی بالینی شاهددار تصادفی شده...
[ 3 ] - بررسی ارتباط الگوهای غذایی غالب با بروز بیماری مزمن کلیه در افراد مبتلا به فشار خون بالا: مطالعه‌ی قند و لیپید تهران
مقدمه: مطالعه‌ی حاضر با هدف بررسی ارتباط الگوهای غذایی با بروز بیماری مزمن کلیه در افراد مبتلا به فشار خون بالا طراحی شد. مواد و روشها: این مطالعه‌ی طولی بر روی 1521 فرد مبتلا به پیش پرفشاری خون و پرفشاری خون شرکت کننده در مرحله‌ی چهارم مطالعه‌ی قند و لیپید تهران با سن≥ 27 سال که در شروع مطالعه فاقد بیماری مزمن کلیه بودند، انجام شد. دریافت رژیمی افراد با استفاده از پرسش‌نامه‌ی بسامد خوراک معتب...
[ 4 ] - نقش پروبیوتیکها در کنترل گلایسمیک و وزن بدن در دیابت نوع 2: مروری ساختاریافته بر مطالعات انسانی و حیوانی
مقدمه: بررسی اثر پروبیوتیکها بر شاخصهای قند خون و تغییرات وزن در بیماری دیابت در سال‌های اخیر فزونی یافته است. بنابراین مطالعه حاضر به مقایسه تمام مطالعات حیوانی و انسانی مرتبط در این زمینه پرداخته است. مواد و روشها: مطالعه حاضر با جستجو در پایگاه‌های اطلاعاتی تا ماه می 2014، به بررسی اثر پروبیوتیکها بر قند خون ناشتا، قند خون 2 ساعته، هموگلوبین گلیکوزیله، انسولین خون، مقاومت انسولینی و ...
[ 5 ] - اثر دریافت ماست پروبیوتیک و معمولی بر شاخصهای قند خون و مقاومت انسولینی در بیماران مبتلا به دیابت نوع 2: کارآزمایی بالینی کنترل‌دار تصادفی شده
مقدمه: ماست پروبیوتیک جز غذاهای فراسودمند محسوب میشود و اثرات مفیدی بر سلامت افراد دارد. در چندین پژوهش حیوانی اثر پروبیوتیکها در کاهش قند خون و به تاخیر انداختن بروز افزایش قند خون و مقاومت انسولینی گزارش شده است. با توجه به شیوع روز افزون دیابت نوع 2، پژوهش کنونی با هدف بررسی تاثیر ماست پروبیوتیک بر شاخصهای قند خون و مقاومت انسولینی در بیماران مبتلا به دیابت نوع 2 انجام شد. مواد و روشها:...
[ 6 ] - ارتباط پوسیدگی دندان با نمایه توده بدنی و عادات غذایی در کودکان مراجعه کننده به کلینیک دندانپزشکی دانشگاه علوم پزشکی تبریز
Regarding to the importance of food habits and the probable role of obesity in dental caries, this study was done to assess the relationship between teeth decay index in children and body mass index, and food habits in dentistry clinic of Tabriz university of medical sciences. Materials and Methods: In this cross-sectional analytic study 202 children aged 3-12 years old were selected randomly. ...
[ 7 ] - Worldwide trends in scientific publications on association of gut microbiota with obesity
Objective(s): Recent evidence has shown underlying roles of gut dysbiosis and metabolic endotoxemia in obesity and its complications. Despite the large number of experimental and clinical researches performed on gut microbiota and obesity, no bibliometrics’ study has been conducted so far. We aimed to assess the trend of global scientific publications in the field of gut microbiota and obesity....
[ 8 ] - Gut Microbiota Composition in Obese and Normal Weight Adults in Iran
Background and purpose: Increasing prevalence of obesity over the past few decades constitutes a global health challenge. Recent evidence suggests that gut microbiota may contribute to weight control. So, the present study aimed at comparing the frequency of different bacteria in gut microbiota between obese and normal weight people in Iran. Materials and methods: Thirty normal weight (BMI of ...
[ 9 ] - The Microbiome in Precision Medicine: A New Approach to Cancer Treatment
Precision medicine is a new approach in medical sciences aimed at individualizing treatment, reducing adverse drug reactions (ADRs), and decreasing health care costs. Precision medicine is also able to maintain the health of individuals by regulating their composition of microorganisms (microbiota) using specific methods. Microbiota is the total stock of microbial species in different organs of...
[ 10 ] - The Role of Probiotics in Management of Infected Diabetic Foot Ulcers
Diabetic foot ulcer (DFU) is one of the common reasons for non-traumatic amputation of the lower limbs, which requires proper diagnosis, proper collection of specimens, careful selection of antibiotics, treatment of infection based on the disease condition, quick decision about whether or not surgery is necessary and other types of wound care. Probiotics are suggested as non-pathogenic microor...
[ 11 ] - Comparing the Effects of Live and Pasteurized Akkermansia muciniphila on Management of Obesity and Diabetes
Diabetes and obesity are among the most important metabolic disorders which are of worldwide concern. Today, it has been proven that the diversity and composition of the intestinal microbiota play a key role in the incidence and control of metabolic diseases via regulating the metabolism and immune responses of the host. Previous studies reported links between Akkermansia muciniphila, a commen...
[ 12 ] - The Role of Intestinal Microbiota in Cognitive Disorders
Cognitive disorders are one of the major public health issues in older population worldwide. Problems in forming and storing new memories, short-term memory impairment, and other cognitive problems are common symptoms of cognitive disorders that have no definite treatment yet. Recent studies have shown an association between gut microbiota and cognitive impairments described as microbiota-gut-...
[ 13 ] - Beneficial Effects of Inactive and Non-Viable Probiotics on Health
According to the World Health Organization, viable probiotics could have health effects. However, in recent years, many benefits have been observed through application of inactive and non-viable cells of microbes or their metabolites. Therefore, probiotics could be defined as viable, inactive, or non-viable microbial cells or cell extracts that have beneficial health effects on the host. Based...
[ 14 ] - Diet-Microbiota Interactions: A New Approach to Personalized Nutrition
Personalized nutrition is a new approach in medical sciences that is based on genetic profile, individual needs, and environmental conditions considering health status and chronic diseases of every person. Studies have shown that genetic differences cannot solely justify various responses to medications and diets, and other important factors including gut microbiota are also involved. Human bo...
[ 15 ] - Extracellular Vesicles Derived from Gastrointestinal Microbiota: A New Approach to Clinical Studies
Extracellular vesicles, naturally released from all cell types including bacteria, are of great importance in medical microbiology due to transporting a variety of biomaterials, enzymes, and virulence factors, regulating immunity, and having roles in colonization and initiation of signaling pathways. These vesicles are also secreted from microbiota in the gastrointestinal tract and affect the h...
[ 16 ] - Role of Gut Microbiome in Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a complex endocrine disorder that affects 8-13% of women at reproductive age worldwide. This disorder is usually associated with menstrual disorders, infertility, obesity, and insulin resistance. The underlying cause of this syndrome is unknown, however in recent years, researchers have shown an association between intestinal microbiota alterations )dysbiosi...
[ 17 ] - Analysis of Scientific Products about Microbiota and Covid-19: A Scientometric Study
Background and purpose: Gastrointestinal symptoms along with respiratory symptoms recorded in patients with Covid-19 indicate the role of microbiota in this disease. The purpose of this scientometric study was to assess the articles published on the relationship between microbiota and Covid-19 in order to control the pandemic by reaching new strategies. Materials and methods: Relevant articl...
[ 18 ] - Clinical application of gut microbiota metabolites: A novel opportunity in personalized medicine
Nowadays, metabolomics studies are performed with different approaches to identify biomarkers, clarify the underlying mechanisms of diseases and achieve novel treatment strategies. In this context, gut microbiota-derived metabolites are known as one of the most important mediators of gut microbiota effects on human health and various diseases. Due to the inefficiency of conventional therapies i...
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