نتایج جستجو برای: mesobuthus eupeus
تعداد نتایج: 240 فیلتر نتایج به سال:
Scorpions of the genus Mesobuthus represent a useful terrestrial model system for studying molecular evolution. They are distributed on several Aegean islands and the adjacent mainland, they are believed to have low rates of dispersal, and evolutionary divergence dates of taxa are available based on biogeographic events that separated islands from each other and the mainland. Here, we present d...
The crude venom of Mesobuthus gibbosus which is widely distributed in the Mediterranean region of Anatolia were investigated for its cytotoxic and gelatinolytic activities in vitro. Cytotoxic effects of the crude venom were examined in three different cell lines by MTT assay. 5RP7 is H-ras activated mouse fibroblasts, CO25 is N-ras activated mouse myoblasts and A549 is human adenocarcinomas cel...
Animal venoms are a mixture of peptides and proteins that serve two basic biological functions: predation and defense against both predators and microbes. Antimicrobial peptides (AMPs) are a common component extensively present in various scorpion venoms (herein abbreviated as svAMPs). However, their roles in predation and defense against predators and potential as drugs are poorly understood. ...
BmK IT-AP is an excitatory insect-specific beta-toxin with analgesic effect from the Chinese scorpion Buthus martensii Karsch (BmK) and consists of 72 residues cross-linked by four disulfide bridges. The crystal structure of BmK IT-AP has been determined at a resolution of 2.6 A by molecular replacement. Compared with the mammal-selective alpha-toxins consisting of 64 residues from the scorpion...
Non-proline cis peptide bonds have been observed in numerous protein crystal structures even though the energetic barrier to this conformation is significant and no non-prolyl-cis/trans-isomerase has been identified to date. While some external factors, such as metal binding or co-factor interaction, have been identified that appear to induce cis/trans isomerization of non-proline peptide bonds...
By screening extracts of venom from the Asian scorpion Buthus martensii Karsch (BmK) for their abilities to activate opioid receptors, we have identified BmK-YA, an amidated peptide containing an enkephalin-like sequence. BmK-YA is encoded by a precursor that displays a signal sequence and contains four copies of BmK-YA sequences and four of His(4)-BmK-YA, all flanked by single amino acid resid...
Representing a basal branch of arachnids, scorpions are known as 'living fossils' that maintain an ancient anatomy and are adapted to have survived extreme climate changes. Here we report the genome sequence of Mesobuthus martensii, containing 32,016 protein-coding genes, the most among sequenced arthropods. Although M. martensii appears to evolve conservatively, it has a greater gene family tu...
Since the publication of the ground-breaking "Catalogue of the scorpions of the world (1758-1998)" (Fet et al. 2000) the number of species in the scorpion genus Buthus Leach, 1815 has increased 10-fold, and this genus is now the fourth largest within the Buthidae, with 52 valid named species. Here we revise and update the available information regarding Buthus. A new combination is proposed: Bu...
عقرب گزیدگی یکی از خطرهای کلان بهداشت و سلامت انسان و حیوانات به ویژه در مناطق گرمسیری است. کژدم مزوبوتوس یوپئوس یکی از شش کژدم مهم و خطرناک در منطقهی خوزستان و ایران است. در این پژوهش، اثرات سم این کژدم بر تابلوی خونی و شکنندگی اسمزی گلبولهای قرمز (OF) و همچنین مقایسهی کارایی آنتیونوم پلیوالان و مادهی آنتیاکسیدان کوارستین در حفاظت از گلبولهای قرمز در موش صحرایی مورد بررس...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید