International asset demands are functions of expected returns. Optimal portfolio theory tells us that the coetlicients in this relationship depend on the variance-covariance matrix of real returns. But previous estimates of the optimal portfolio (1) assume expected returns constant and (2) are not set up to test the hypothesis of mean-variance optimization. We use maximum likelihood estimation ...

Stakeholders in the science system need to decide where to place their bets. Example questions include: Which areas of research should get more funding? Who should we hire? Which projects should we abandon and which new projects should we start? Making informed choices requires knowledge about these research options. Unfortunately, to date research portfolio options have not been defined in a c...

Corresponding author: Seonghoon Ko, M.D., Ph.D., Department of Anesthesiology and Pain Medicine, Chonbuk National University Medical School and Hospital, 634-18, Keumam-dong, Jeonju 561-712, Korea. Tel: 82-63-250-1979, Fax: 82-63-250-1240, E-mail: [email protected] This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creati...

Introduction Management of intermediate and long-term (more than 30 60 minutes) anesthetic procedures most commonly involves the use of inhalational anesthetic methods in many species. Over the last 40 years, this has become true also for equine anesthesia. The delivery of anesthetic drugs via the lungs offers some advantages in part caused by the pharmacokinetics of the volatile agents in clin...

Relevance: Among patients who have undergone extensive surgical interventions under general anesthesia with artificial ventilation (ventilator), various postoperative respiratory complications of an obstructive or restrictive nature are often found
 The study aimed to generalizе current data from systematic reviews, meta-analyses, and scientific publications on the use preventive therapeut...

this survey investigates post general anesthesia complications in recovery room in patients undergoing elective surgery in one of the hospitals of iran university of medical sciences.

Let X ∈ R denote a random stock market return vector, where Xj is the value of a one unit investment in stock j at the end of the trading day. We require that Xj ≥ 0 for j = 1, 2, . . . , m, that is, an investor cannot lose more than the invested capital. Let b, bj ≥ 0, ∑m j=1 bj = 1, denote a portfolio, that is, an allocation of investor’s capital across the investment alternatives. Let B deno...

discussion recently about life-cycle funds and their role in providing a secure retirement income for older Americans. These funds, which gradually shift account assets from broad-based stock funds to bond funds as a participant ages, are becoming an important vehicle for retirement savings. This policy brief explores the economic rationale behind the life-cycle approach and the advantages and ...