Background: Morality is a human experience that every person needs in his normal life to have moral virtue that he relies on. Ethics is a core tool or life skill that is an integral dimension of well-being. Moral well-being can lead to the reduction of conflicts and emotional divorce. Therefore, the present research was conducted with the aim of investigating the relationship between moral well...

A surface plasmon resonance imaging-based Ni(2+)-iminodiacetic acid-coated gold chip system was developed to enable specific detection of a hexahistidine-tagged recombinant protein in crude extracts or in column chromatography fractions. This system is especially advantageous for high-throughput analysis of multiple proteins.

Fluorescent probes are essential for the exploration of protein function, detection of molecular interactions, and conformational changes. The nitrilotriacetic acid derivatives of different chromophores were successfully used for site-selective noncovalent fluorescence labeling of histidine-tagged proteins. All of them, however, suffer from the same drawback--loss of the fluorescence upon bindi...

Affinity tags have become powerful tools from basic biological research to structural and functional proteomics. They were widely used to facilitate the purification and detection of proteins of interest, as well as the separation of protein complexes. Here, we mainly discuss the benefits and drawbacks of several affinity or epitope tags frequently used, including hexahistidine tag, FLAG tag, S...

Some argue that humans should enhance their moral capacities by adopting institutions that facilitate morally good motives and behaviour. I have defended a parallel claim: that we could permissibly use biomedical technologies to enhance our moral capacities, for example by attenuating certain counter-moral emotions. John Harris has recently responded to my argument by raising three concerns abo...

Richard E. Redding (March 2001) is to be complimented for calling attention to the incongruity between the narrowness of psychology’s liberal sociopolitical mentality and its simultaneous reverence for cultural diversity. His justified criticism, however, failed to come to grips with the moral and methodological issues underlying his complaint. Is his objection solely directed at the restricted...