2010;74;691 Neurology Hans D. Katzberg, Ahmir H. Khan and Yuen T. So of Neurology Technology Assessment Subcommittee of the American Academy evidence-based review) : Report of the Therapeutics and Assessment: Symptomatic treatment for muscle cramps (an January 10, 2013 This information is current as of http://www.neurology.org/content/74/8/691.full.html located on the World Wide Web at: The onl...

High-frequency oscillations (HFO) have been suggested to reflect the activity of thalamocortical and/or intracortical neurons bursting at high frequencies. These circuits seem to be involved in pathophysiological mechanisms of focal dystonia. In healthy subjects, we characterized the spectrotemporal properties of HFO patterns evoked by dominant-hand median-nerve stimulation, using magnetoenceph...

The tension produced by the cramp evoked in the adductor pollicis muscle by repetitive stimuli to the nerve (20/s for 50 s) and by full voluntary effort in the brachial biceps was measured in a patient with McArdle's disease. The contracture was 17% of the peaktetanic tension, and was not associated with action potentials. Twitches superimposed on the contracture were at most diminished to half...

Recently an article provided patient perspectives on therapies and perceived effectiveness in preventing muscle cramps. However, there are few studies evaluating physicians' point of view in the management of this common symptom. In our study, we studied physician practice patterns in the treatment of muscle cramps by surveying a group of neurologists in Canada. We demonstrated that most physic...

Seven of the nine people present at the barbeque developed diarrhea with abdominal cramps between 3 to 10 days following the barbeque (Fig.1). Two had bloody diarrhea. The two children with bloody diarrhea (an 11-month-old male and a 15-year-old female) and one with non-bloody diarrhea (a 4-year-old female) sought medical attention. There was sufficient stool from two of these children (the 11-...

The study by Hallegraeff et al (2012) was of unusual interest to us, having nicely supported our uncontrolled observation that nocturnal cramps could often be prevented by prophylactic calf stretching (Daniell 1979). Differences between our stretching regimen and that which they used included the number of muscle groups stretched, the position in which each stretch was performed, and the freque...

Salmonella enterica serovar Typhimurium uses two-component regulatory systems (TCRSs) to respond to environmental stimuli. Upon infection, the TCRSs PhoP-PhoQ (PhoPQ) and PmrA-PmrB (PmrAB) are activated by environmental signals detected in the lumen of the intestine and within host cells. TCRS-mediated gene expression leads to upregulation of genes involved in lipopolysaccharide (LPS) modificat...