We describe a case of isolated primary laryngeal leishmaniasis in an immunocompetent Italian patient with a previous medical history negative for visceral or cutaneous leishmaniasis, presenting with hoarseness. We also summarize the epidemiological, clinical, and diagnostic features and the therapeutic management of other cases of laryngeal leishmaniasis in immunocompetent subjects, described i...

Among parasitic diseases, morbidity and mortality caused by leishmaniasis are surpassed only by malaria and lymphatic filariasis. However, estimation of the leishmaniasis disease burden is challenging, due to clinical and epidemiological diversity, marked geographic clustering, and lack of reliable data on incidence, duration, and impact of the various disease syndromes. Non-health effects such...

Large-scale field trials were performed in an endemic focus of cutaneous leishmaniasis in both urban and rural settlements of Sanliurfa City, SE Anatolia, Turkey, to evaluate the efficacy of insecticide impregnated bednets. An intervention field trial promoting the use of K-OTAB (deltamethrin-tablet formulation) impregnated bednets by the local inhabitants of five quarters for cutaneous leishma...

A vaccine against different forms of leishmaniasis should be feasible considering the wealth of information on genetics and biology of the parasite, clinical and experimental immunology of leishmaniasis, and the availability of vaccines that can protect experimental animals against challenge with different Leishmania species. However, there is no vaccine against any form of leishmaniasis for ge...

Leishmaniasis is a parasitic disease caused by various species of Leishmania, a unicellular kinetoplastid protozoan flagellate. It manifests mainly in 3 clinical forms; visceral leishmaniasis (VL), cutaneous leishmaniasis (CL) and mucocutaneous leishmaniasis (MCL), of which VL is the most severe form of the disease. VL is lethal if untreated and spontaneous cure is extremely rare. Cutaneous lei...

Leishmaniasis is a clinically heterogeneous syndrome caused by intracellular protozoan parasites of the genus Leishmania. The clinical spectrum of leishmaniasis encompasses subclinical (not apparent), localized (skin lesion), and disseminated (cutaneous, mucocutaneous, and visceral) infection. This spectrum of manifestations depends on the immune status of the host, on the parasite, and on immu...

In Morocco, as in most countries around the Mediterranean, leishmaniasis is an important public health problem. The situation has become worrying since the 1970’s and continues to be more complicated. The objective of this work was to realize a historical overview of the classification, evolution, and dispersion of Leishmania parasites and Sandflies in Morocco. The status of the different leish...

Leishmaniasis is a neglected tropical disease infecting world’s poorest population in over 90 countries throughout Asia, Africa, the Middle East, and Central South Africa. An underestimated 700,000 to one million new cases occur annually. refers spectrum of diseases caused by parasite, Leishmania, transmitted bite infected sandflies. Of three major syndromes (cutaneous, mucosal visceral) leishm...

Background and objective:Many biochemical features of sulfur mustard (SM) intoxication remained unknown. So far, the direct association between biochemical parameter changes and ocular problems in patients exposed to SM is not evaluated.The current study aimed at evaluating the associations between the ocular findings in patients with SM intoxication and the changes of...

background: leishmaniasis is an obligate intercellular protozoon that affects animals and human. it has zoonosis and/or anthroponosis transmission. human and veterinary medicine, environmental science and wildlife conservation special­ists have many commonalities in case of visceral leishmaniasis. still the above disciplines respond against leishmaniasis in a separate way.   the aim of this re­...