OBJECTIVE To determine the incidence of potentially malignant oral lesions, and evaluate and correlate their clinical and pathological aspects. METHODS The sample consisted of cases clinically diagnosed as oral leukoplakia, oral erythroplakia, erythroleukoplakia, actinic cheilitis, and oral lichen planus treated at a diagnostic center, between May 2012 and July 2013. Statistical tests were co...

background: tumor markers are substances, which quantitatively changes in serum, during the tumor development, one such tumor marker is serum β2-microglobulin (β2-m). the aim of this study was to establish the role of β2-m as a biochemical parameter for diagnosis and prognosis of oral carcinoma by estimation of serum β2-m levels in potentially malignant lesions, conditions, and oral squamous ce...

Non-Hodgkin lymphoma (NHL) represents the third most common group of malignant lesions of the oral cavity, following squamous cell carcinomas and salivary gland neoplasms. It accounts for 3-5% of all malignant lesions of the oral cavity [1]. Further, only 1% of all lymphomas are primary oral cavity lymphoma. Non-Hodgkin’s lymphoma of the tongue is extremely rare. It can arise from Waldeyer’s ri...

epitheloid hemangioendothelioma (ehe) is an uncommon angiocentric neoplasm of intermediate malignant potential. this tumor is frequently seen in the lungs and liver, but its presentation in the oral cavity is rare. in the oral cavity, gingival region is the common sites of occurrence. we report a rare case of epitheloid hemangioendothelioma in a 48-year-old male, presenting as a growth in the u...

Owing to recent advances in diagnostic and surgical techniques for cancer, a patient diagnosed with two or more neoplasms is not rare. We report on the case of a 58-year-old male with multiple primary malignant neoplasms, who suffered from three histological types of malignant neoplasm in six organs, namely the glottis, renal pelvis, urinary bladder, oral floor, prostate, and esophagus in chron...

Early diagnosis is vital for effective treatment of oral squamous cell carcinoma (OSCC). The optimal time for clinical intervention is prior to malignancy when patients present with oral potentially malignant lesions such as leukoplakia or erythroplakia. Transformation rates for oral dysplasia vary greatly and more rigorous methods are needed to predict the malignant potential of oral lesions. ...

Eosinophilia in tissues and/or circulating blood is known to be associated with a wide variety of malignancies but the role of the eosinophil in neoplastic conditions is not known. Using the cheek pouch of the Syrian hamster as an experimental model for oral carcinogenesis, it has recently been shown that eosinophils at sites of developing oral cancer express the multifunctional cytokine, trans...

Oral cancer is one of the most prevalent cancers and one of the 10 most common causes of death in the world. Epidemiological studies have shown that the prevalence of oral cancer varies from less than 0.1% to over 40% in different parts of the world. Unfortunately, the majority of oral cancers are diagnosed in advanced stages after becoming symptomatic. In comparison with malignant neoplasms at...