Orofacial pain, the main reason why many patients seek dental advice, usually has a local cause--primarily the sequelae of dental caries--but a wide range of diseases, particularly neurological, psychogenic and vascular disorders, can cause orofacial pain. This article will discuss disorders that can present with pain and the neurological, psychogenic and vascular causes of orofacial pain. The ...

Dental providers must determine the presence of orofacial injury, and diagnose and treat dental and orofacial outcomes of trauma caused by motor vehicle collisions. Determination of causation and relation to the trauma is indicated. Dental trauma includes concussion, subluxation and dislocation of teeth, and fracture of teeth and maxillofacial bone, in addition to soft tissue injury that may ca...

Orofacial granulomatosis is a granulomatous disease of orofacial region, which can occur for a variety of reasons. The clinical features are highly variable and sometimes so insidious that signs and symptoms are not frequently severe to cause alarm. The lips are most commonly involved with persistent/recurrent swelling. The medical history is very important as Crohn's disease and sarcoidosis ca...

EEC syndrome is an autosomal dominant disorder with the cardinal signs of ectrodactyly, ectodermal dysplasia, and orofacial clefts. EEC syndrome has been linked to chromosome 3q27 and heterozygous p63 mutations were detected in unrelated EEC families. In addition, homozygous p63 null mice exhibit craniofacial abnormalities, limb truncations, and absence of epidermal appendages, such as hair fol...

Low-power lasers are a group of lasers with a power less than 500 mW and unlike high-power lasers they have no effect on tissue temperature; they produce light-dependent chemical reactions in tissues. The purpose of this study was to review the clinical applications of these lasers and their success rate in different studies in orofacial pains. The articles with the key word “low level laser th...

low-power lasers are a group of lasers with a power less than 250 mw and unlike high-power lasers they have no effect on tissue temperature; they produce light-dependent chemical reactions in tissues. these lasers have analgesic features with their ability to trigger reactions that reduce pain and inflammatory mediators. low-power lasers can also be used instead of needles in acupuncture to dec...

Myopathy and muscular pseudohypertrophy associated with severe congenital hypothyroidism has been described as Kocher Debre Semelaigne syndrome, which is a rare disorder with only a few previously published reports. However, none of these reports have described the orofacial aspects of this syndrome. Here we report one such case, which may provide valuable information to specialists in oral hea...

BACKGROUND Cyclin-dependent kinase 5 (Cdk5) is a unique member of the serine/threonine kinase family. This kinase plays an important role in neuronal development, and deregulation of its activity leads to neurodegenerative disorders. Cdk5 also serves an important function in the regulation of nociceptive signaling. Our previous studies revealed that the expression of Cdk5 and its activator, p35...

Orofacial clefts are the commonest congenital structural anomalies of the lip and/or palate. Beyond cosmetic abnormality children often suffer from feeding difficulties, ear infections, hearing loss, speech and language delay, dental problems and multiple craniofacial/dental surgeries. Present study was conducted to assess DNA damage among children with orofacial clefts. One ml of peripheral bl...