BACKGROUND & OBJECTIVE The conventionally used perioperative glucocorticoid replacement protocol in patients with pituitary tumours is far from optimal. In this study we evaluated the validity of a modified protocol for perioperative glucocorticoid replacement in non-functioning pituitary macroadenomas. METHODS A total of 24 consecutive patients with non functioning pituitary macroadenomas we...

Hypothyroidism There is general agreement that all patients with symptomatic hypothyroidism should receive replacement treatment. MANAGEMENT Thyroxine should be used in the routine management of hypothyroidism. The initial dose should not exceed 0-05 mg daily in patients over 40; an initial dose of 0-1 mg daily may be used in younger patients. The dose should be increased by increments until th...

1863 liter three years before admission. Instead of providing immediate immune globulin replacement on admission, his clinicians remeasured the serum IgG five days later (130 mg per deciliter), and immune globulin replacement was given seven days after admission. The patient died on the 12th hospital day. There is an extensive body of literature supporting the value of intravenous immune globul...

BACKGROUND Inflammation and malnutrition are common in chronic kidney disease (CKD) patients, and plasma concentrations of free amino acids (AAs) in these patients are often abnormal. Malnutrition contributes to alterations in AA concentrations. OBJECTIVE The objective was to study the effects of inflammation on plasma AA concentrations. DESIGN Concentrations of plasma AAs, serum albumin, a...

The problem of the relation of antibodies to normal serum globulins has been approached in the past by comparison of their chemical, physical, and immunological properties in the native state (cf. 1-3). Little information is available, however, on their relative behavior in the denatured state. This paper describes an investigation of the effects of denaturation by guanidine hydrochloride on ce...

introduction:  in patients who underwent surgery to repair tetralogy of fallot, right ventricular dilation from pulmonary regurgitation may be result in right ventricular failure, arrhythmias and cardiac arrest. hence, pulmonary valve replacement may be necessary to reduce right ventricular volume overload. the aim of present study was to assess the effects of pulmonary valve replacement on rig...

BACKGROUND The aim of this study was to perform a clinical assessment of the association between oral lichenoid reactions (OLR) and amalgam restorations and to determine the salivary concentrations of interleukin-6 (IL-6) and IL-8 before and after replacement of the amalgam restorations. METHODS The study included 20 patients with OLR and 20 healthy volunteers, who were examined between 2001 ...

Thirty six male Chall lambs (four-month old and 26  ±1.5 kg body weight) were randomly assigned into four treatments (nine lambs per treatment) to study the effect of Powerfeed® (a commercial mixture made from wheat processing by-product and wheat bran) on weight gain, feed intake, feed conversion ratio, serum sodium and potassium concentration and urine pH. Lambs in control group were fed with...

There has been an increase in the number of individuals seeking testosterone (T) replacement treatment (TRT) due to a decrease in their blood T levels. Prostate cancer (PCa) is also an important issue in the same age group. However, we, urologists, are anxious about PCa development after T treatment. This is because it has been assumed that T may cause PCa or exacerbate insidious PCa which is a...