OBJECTIVE Acetyl-L-carnitine (ALC), a constructive molecule in fatty acid metabolism, is an agent potentially effective for treating peripheral neuropathic pain (PNP). Its effect, however, remains uncertain. We aimed to access the efficacy and safety of ALC for the treatment of patients with PNP. METHODS We searched MEDLINE (1996-2014), EMBase (1974-2014), and CENTRAL (May 2014) up to June 27...

A microbial biosensor consisting of a dissolved oxygen electrode modified with the genetically engineered PNP-degrader Moraxella sp. displaying organophosphorus hydrolase (OPH) on the cell surface for sensitive, selective, rapid and direct determination of p-nitrophenyl (PNP)-substituted organophosphates (OPs) is reported. Surface-expressed OPH works in tandem with the PNP oxidation machinery o...

We expressed a putative β-galactosidase Asac_1390 from hyperthermophilic crenarchaeon Acidilobus saccharovorans in Escherichia coli and purified the recombinant enzyme. Asac_1390 is composed of 490 amino acid residues and showed high sequence similarity to family 1 glycoside hydrolases from various thermophilic Crenarchaeota. The maximum activity was observed at pH 6.0 and 93°C. The half-life o...

TiO2 prepared by a green aqueous sol–gel peptization process is co-doped with nitrogen and zirconium to improve extend its photoactivity the visible region. Two precursors are used: urea triethylamine; (IV) tert-butoxide added as source of zirconia. The N/Ti molar ratio fixed regardless chosen precursor while quantity zirconia set 0.7, 1.4, 2, or 2.8 mol%. performance physico-chemical propertie...

We examined the anaerobic degradation of phenol and the ortho, meta, and para isomers of chlorophenol, methoxyphenol, methylphenol (cresol), and nitrophenol in anaerobic sewage sludge diluted to 10% in a mineral salts medium. Of the 12 monosubstituted phenols studied, only p-chlorophenol and o-cresol were not significantly degraded during an 8-week incubation period. The phenol compounds degrad...

Synthesis of (PNP(R))ReOCl(2) (PNP(R) = (R(2)PCH(2)SiMe(2))(2)N, R = (i)()Pr, Cy, and (t)()Bu) from (Me(2)S)(2)ReOCl(3) and (PNP(R))MgCl is described. Magnesium and H(2) convert (PNP(R))ReOCl(2) first to (PNP(R))ReO(H)(2) and then to (PNP(R))Re(H)(4), the last being an operationally unsaturated species which can bind PMe(3) or p-toluidine. Acyclic alkenes react with (PNP(R))Re(H)(4) at 22 degre...

To develop functionally and nutritionally improved whole soybean curd (WSC), the effects of partial (0 ~ 4%) replacement with pine needle powder (PNP) on the quality characteristics of WSC were investigated. The moisture content and pH ranged from 76.96~77.80% (wet basis) and 6.69~6.74, respectively, with no considerable differences. Lightness significantly decreased with higher PNP content in ...

BACKGROUND Acute lung injury (ALI) induces a coagulation/fibrinolysis imbalance and leads to fibrin deposition. The protein C pathway is an important regulator of the coagulation system and reduces the inflammatory response. The aim of the study was to examine the effects of recombinant human activated protein C (rhAPC) in the early phase of Pseudomonas aeruginosa (Pa)-induced lung injury. ME...

normal 0 false false false en-us x-none ar-sa background: diabetes mellitus (dm) is a common metabolic disorder that can cause various complications including, peripheral neuropathy (pnp). some possible risk-factors such as blood glucose level, hyperglycemia, duration of diabetes, and lipid profiles are assumed to be important in diabetic pnp incidence. the aim of this study is to evaluate the ...