نتایج جستجو برای: pfmdr1
تعداد نتایج: 279 فیلتر نتایج به سال:
Using DNA extracted from 112 parasitised blood blots, we screened for the population marker of chloroquine resistance (CQR) pfcrt K76T in Plasmodium falciparum infections from Guyana. Pfmdr1 mutations S1034C, N1042D, and D1246Y also associated with CQR were surveyed as well in 15 isolates for which the in vitro responses to CQ were known. Results indicate that the pfcrt K76T is ubiquitous in th...
Drug resistance in Plasmodium falciparum is a serious public health threat in the countries where this organism is endemic. Since resistance has been associated with specific single-nucleotide polymorphisms (SNPs) in parasite genes, molecular markers are becoming useful surrogates for monitoring the emergence and dispersion of drug resistance. In this study, a multiplex PCR (mPCR) and oligonucl...
Because of the lack of methods for continuous in vitro culture of Plasmodium vivax, little is known about drug-resistance mechanisms in this malaria-causing parasite. Therefore, identification of all the genes potentially involved in drug resistance and of molecular markers related to drug resistance would provide a framework for studying the incidence and spread of drug-resistant P. vivax stra...
Research was conducted on the molecular survey of drug resistant Plasmodium falciparum malaria among pregnant women attending ante natal care (ANC) at Maryam Abacha Women and Children Hospital (MAWCH) Sokoto, Nigeria from February, 2020 to May, 2020. Blood samples 200 who came for ANC in were collected Questionnaire administered. Thin thick blood film microscopy mono clonal antibody specific RD...
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