نتایج جستجو برای: plga nanosphere

تعداد نتایج: 4541  

2015
Cristian Vilos Luis A. Velasquez Paula I. Rodas Katherine Zepeda Soung-Jae Bong Natalia Herrera Mario Cantin Felipe Simon Luis Constandil

Drug delivery systems based on polymeric microparticles represent an interesting field of development for the treatment of several infectious diseases for humans and animals. In this work, we developed PLGA microparticles loaded with ceftiofur (PLGA-cef), a third- generation cephalosporin that is used exclusively used in animals. PLGA-cef was prepared by the double emulsion w/o/w method, and ex...

2014
Hoon You Eun-Ung Lee You-Kyoung Kim Bum-Chul Kim Jin-Young Park Hyun-Chang Lim Jung-Seok Lee InSup Noh Ui-Won Jung Seong-Ho Choi

BACKGROUND The aim of this study was to evaluate the biocompatibility and resorption pattern in three-layer poly (lactide-co-glycolide) (PLGA) membrane according to the concentrations of hyaluronic acid (HA) hydrogel in rabbit calvarial defect model. Four standardized circular defects with 8 mm diameter were created on the four rabbit calvarium. Three-layer PLGA membranes (5% and 10% HA gel) we...

Journal: :European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2008
Chunqiang Guo Richard A Gemeinhart

Polyelectrolyte-coated nanoparticles or microparticles interact with bioactive molecules (peptides, proteins or nucleic acids) and have been proposed as delivery systems for these molecules. However, the mechanism of adsorption of polyelectrolyte onto particles remains unsolved. In this study, cationic poly(lactide-co-glycolide) (PLGA) nanoparticles were fabricated by adsorption of various conc...

Journal: :Journal of biomedical materials research. Part A 2007
Bin Duan Lili Wu Xiaoyan Yuan Zhen Hu Xiulan Li Yang Zhang Kangde Yao Min Wang

Hybrid nanofibrous membranes of poly(lactic-co-glycolic acid) (PLGA) and chitosan with different chitosan amounts (32.3, 62.7, and 86.5%) were fabricated via a specially designed electrospinning setup consisting of two sets of separate syringe pumps and power supplies. After soaking in chloroform overnight to dissolve PLGA, the amount of chitosan in the hybrid membranes was determined. The stru...

Journal: :Magnetic resonance in medicine 2011
Michael K Nkansah Durga Thakral Erik M Shapiro

Biodegradable, superparamagnetic microparticles and nanoparticles of poly(lactide-co-glycolide) (PLGA) and cellulose were designed, fabricated, and characterized for magnetic cell labeling. Monodisperse nanocrystals of magnetite were incorporated into microparticles and nanoparticles of PLGA and cellulose with high efficiency using an oil-in-water single emulsion technique. Superparamagnetic co...

2017
Juqun Xi Lanyue Da Changshui Yang Rui Chen Lizeng Gao Lei Fan Jie Han

Nanoparticle drug delivery carriers, which can implement high performances of multi-functions, are of great interest, especially for improving cancer therapy. Herein, we reported a new approach to construct Mn2+-coordinated doxorubicin (DOX)-loaded poly(lactic-co-glycolic acid) (PLGA) nanoparticles as a platform for synergistic chemo-photothermal tumor therapy. DOX-loaded PLGA (DOX/PLGA) nanopa...

2016
Shenglian Yao Huiying Liu Shukui Yu Yuanyuan Li Xiumei Wang Luning Wang

The development of modern therapeutics has raised the requirement for controlled drug delivery system which is able to efficiently encapsulate bioactive agents and achieve their release at a desired rate satisfying the need of the practical system. In this study, two kind of aqueous model drugs with different molecule weight, Congo red and albumin from bovine serum (BSA) were nano-encapsulated ...

The potential of PLGA-nanoparticles as a carrier of amphotericin B and doxorubicin against visceral leishmaniasis was evaluated by macrophage-mediated drug targeting approach. PLGA-nanoparticles were modified by coating them with macrophage-specific ligand-lectin. Prior to in-vitro studies, characterization studies were carried out systematically include particle size, surface morphology, perce...

Journal: :international journal of nano dimension 0
k. talukdar department of physics, nit durgapur, west bengal, india. a. k. mitra department of physics, nit durgapur, west bengal, india.

the efficient detection of charged biomolecules by biosensor with appropriate semiconducting nanomaterials and with optimum device geometry has caught tremendous research interest in the present decade. here, the performance of various label-free electronic biosensors to detect bio-molecules is investigated by simulation technique. silicon nanowire sensor, nanosphere sensor and double gate fiel...

2017
Lirong Yang Evelyn Bracho-Sanchez Lawrence P Fernando Jamal S Lewis Matthew R Carstens Craig L Duvall Benjamin G Keselowsky

Poly(lactic-co-glycolic acid) (PLGA) based microparticles (MPs) are widely investigated for their ability to load a range of molecules with high efficiency, including antigenic proteins, and release them in a controlled manner. Micron-sized PLGA MPs are readily phagocytosed by antigen presenting cells, and localized to endosomes. Due to low pH and digestive enzymes, encapsulated protein cargo i...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید