نتایج جستجو برای: pol were there consequently

تعداد نتایج: 4252592  

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2005
Quynh-Thu Le Carol D Jones Tsz-Kok Yau Haider A Shirazi Priscilla H Wong Ella N Thomas Bruce K Patterson Anne W M Lee James L Zehnder

PURPOSE To compare the performance of three PCR assays in measuring circulating Epstein-Barr virus (EBV). DNA levels in nasopharyngeal carcinoma patients and to confirm its prognostic significance. EXPERIMENTAL DESIGN Plasma from 58 newly diagnosed nasopharyngeal carcinoma patients were collected before, during, and every 3 to 6 months after radiotherapy. EBV DNA levels were determined by rea...

Journal: :Cancer research 2001
J O-Wang K Kawamura Y Tada H Ohmori H Kimura S Sakiyama M Tagawa

DNA polymerase kappa (Pol kappa) is a newly identified low-fidelity polymerase implicated in spontaneous and DNA damage-induced mutagenesis. As an initial study to investigate its possible involvement in tumorigenesis, we compared the expression level of Pol kappa in tumors and adjacent nontumorous tissues by Northern blot, semiquantitative RT-PCR, and Western blot analyses. In this study, pair...

2004
Jin Yang Zhiwen Chen Yang Liu Robert J. Hickey Linda H. Malkas

The recently discovered human enzyme DNA polymerase (pol ) has been shown to have an exceptionally high error rate on artificial DNA templates. Although there is a considerable body of in vitro evidence for a role for pol in DNA lesion bypass, there is no in vivo evidence to confirm this action. We report here that pol expression is elevated in breast cancer cells and correlates with a signific...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه فردوسی مشهد - دانشکده ادبیات و علوم انسانی 1394

abstract previous studies on willingness to communicate (wtc) have shown the influence of many individual or situational factors on students’ tendency to engage in classroom communication, in which wtc has been viewed either at the trait-level or situational level. however, due to the complexity of the notion of willingness to communicate, the present study suggests that these two strands are ...

2009
Eduardo Mascareno Irena Manukyan Dipak K. Das M. A. Q. Siddiqui

In order to understand the transcriptional mechanism that underlies cell protection to stress, we evaluated the role of CLP-1, a known inhibitor of the transcription elongation complex (pTEFb), in CLP-1 +/- mice hearts. Using the isolated heart model, we observed that the CLP-1 +/- hearts, when subjected to ischaemic stress and evaluated by haemodynamic measurements, exhibit significant cardiop...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شهید چمران اهواز - دانشکده ادبیات و علوم انسانی 1389

this study purported to compare and contrast the use of self-mention and evidentials as two mtadiscourse features in opinion columns of persian and english newspapers. the theoretical basis of this study is the idea that metadiscourse features vary across cultural boundaries. for this purpose, 150 persian and 150 english opinion columns were collected based on three factors of topic, audience a...

Journal: :Cancer research 2004
Jin Yang Zhiwen Chen Yang Liu Robert J Hickey Linda H Malkas

The recently discovered human enzyme DNA polymerase iota (pol iota) has been shown to have an exceptionally high error rate on artificial DNA templates. Although there is a considerable body of in vitro evidence for a role for pol iota in DNA lesion bypass, there is no in vivo evidence to confirm this action. We report here that pol iota expression is elevated in breast cancer cells and correla...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه الزهراء - دانشکده ادبیات، زبانهای خارجی و تاریخ 1389

recent years have witnessed an increased attention to form focused instruction and consciousness raising activities (ellis, 2002; doughty & williams, 1998) on the one hand and extensive and meaningful exposure to the target language (klapper & rees, 2003; day & bamford, 1998) on the other. due to significance attributed to above mentioned issues by scholars, this study attempted to bridge them ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه اصفهان - دانشکده زبانهای خارجی 1390

the purpose of this study was to investigate iranian efl learners’ beliefs about the role of rote learning (rl) in vocabulary learning strategies; besides, the study examined if english proficiency would influence learners’ vocabulary learning strategy use. this study addresses the need for a clear understanding of the role of rl in efl vocabulary learning by looking at iranian efl learners’ ow...

Journal: :Pediatrics 2014
Andrew N Williams Raman M Sharma

Until recently, physician–historians of pediatrics have generally assumed that “pediatrics as a specialized branch of medicine had no real existence before the middle of the nineteenth century.”1 This may be true if we equate pediatrics with professional organizations and specialized children’s hospitals.2,3 But as a body of knowledge and practices addressing the sick child, pediatrics has a mu...

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