Background: Pain and shivering are two unpleasant problems in postoperative period. Various techniques are used to alleviate the postoperative shivering and pain.  We compared the preemptive prescription of a single dose of intravenous meperidine and ketorolac on postoperative pain and shivering in patients undergoing cesarean section with spinal anesthesia. Methods: One hundred and ...

Background: Preemptive analgesia is a method to provide effective pain relief after the surgery. This study was designed compare effects of single analgesic Ketamine intravenous (IV) versus combination low dose and Parecoxib IV as preemptive multimodal in patients undergoing Laparoscopic Cholecystectomy. Methods: prospective, randomized, double blind 48 laparoscopic cholecystectomy. The populat...

BACKGROUND Although early reviews of clinical findings were mostly negative, there is still a widespread belief for the efficacy of preemptive analgesia among clinicians. In this study, we evaluated whether the preemptive use of ketamine decreases post operative pain in patients undergoing appendectomy. METHODS In double-blind, randomized clinical trials, 80 adult male patients undergoing an ...

PURPOSE To evaluate the preemptive analgesia effects of ketamine for postoperative pain. METHODS PubMed, EMBASE and Cochrane Library were searched to identify randomized controlled trials (RCTs) involved in ketamine for preemptive analgesic up to March 2013. The relative risk (RR) or mean difference (MD) as well as the confounding 95% confidence interval (CI) were calculated by the Revman 5.0...

BACKGROUND Uncontrolled postoperative pain, characteristic to abdominal hysterectomy, results in multiple complications. One of the methods for controlling postoperative pain is preemptive analgesia. Gabapentin and tramadol are both used for this purpose. OBJECTIVES This study aims to compare the effects of tramadol and gabapentin, as premedication, in decreasing the pain after hysterectomy. ...

INTRODUCTION Newer generation lithotriptors have been modified to induce less pain. We evaluated factors contributing to post-shock wave lithotripsy (SWL) pain and assessed potential benefits of preemptive analgesia using Rofecoxib, a COX-II inhibitor, and potential effects on stone passage rates. MATERIALS AND METHODS Sixty-nine patients were evaluated. Thirty-eight percent were women and 62...

Melatonin has been suggested as a new natural pain killer in inflammatory pain and during surgical procedures. We designed this randomized double-blind controlled study to evaluate the analgesic efficacy and also optimal preemptive dose of melatonin in patients undergoing cesarean section under spinal anesthesia.One hundred twenty patients scheduled for cesarean section under spinal anesthesia ...

OBJECTIVE The aim of this study was to compare preemptive analgesia of oral ketorolac plus submucous local placebo with oral ketorolac plus submucous local tramadol after impacted mandibular third molar surgery. STUDY DESIGN A double-blind, randomized, placebo-controlled clinical trial was conducted. Patients were randomized into two treatment groups (n = 15 per group): group A, oral ketorola...

BACKGROUND Dextromethorphan (DM), the D-isomer of the codeine analogue levorphanol, is a weak, noncompetitive N-Methyl-D-Aspartate (NMDA) receptor antagonist. It has been suggested that NMDA receptor antagonists induce preemptive analgesia when administrated before tissue injury occurs, thus decreasing the subsequent sensation of pain. METHOD The study was conducted in the Dr. Ali Shariati Ho...