Background: Diabetes mellitus constitutes a significant risk for the fetus if present in pregnant woman. Tissue Doppler imaging (TDI) is less dependent on loading conditions, so it more accurate assessment of cardiac function and can detect subclinical fetal dysfunction. The aim this work was to assess heart functional abnormalities (left ventricular systolic diastolic function, right function)...

Diabetes mellitus complicates 3–5% of all pregnancies and is a major cause of perinatal morbidity and mortality, as well as maternal morbidity. The availability of a variety of new insulins, the insulin pump, and self-monitoring of blood glucose have revolutionized the care of the pregnancy complicated by diabetes mellitus. However, challenges remain in caring for the pregnant patient with preg...

Aims – To examine the changes in glycaemic excursions which occur during pregnancy using continuous glucose monitoring and to compare patterns of glycaemia in pregnant women with type 1 and type 2 diabetes. Research design and methods – Observational data analysis from a prospective randomised study of continuous glucose monitoring in 57 women with pregestational type 1 (n=40) or type 2 diabete...

Introduction: Abnormal pregestational and gestational maternal nutritional status is an undeniable health problem which can result in changes interfere fetal conditions. Objective: To analyze the influence of pre-pregnancy on mother-newborn pair outcomes. Methods: This observational, analytical, cross-sectional study carried out a public Maternity Hospital Joinville, SC, Brazil. A total 1,670 p...

Autism spectrum disorder (ASD) affecting about 1% of all children is associated, in addition to complex genetic factors, with a variety of prenatal, perinatal and postnatal etiologies. We discuss the known associated prenatal factors affecting the fetus throughout pregnancy; whenever relevant, also summarize some animal data. Among the maternal diseases in pregnancy associated with ASD are preg...

The overall aim ofthe diabetic mother, her relatives and all members of the health care team is the safe delivery of a normal, healthy infant at term, preferably by vaginal delivery. This should be achieved with the minimum psychological and physical trauma, inconvenience and risk to the mother. Seen from another angle, avoidance of the many adverse pregnancy outcomes is the primary purpose of ...

As glargine, an analog of human insulin, is increasingly used during pregnancy, a meta-analysis assessed its safety in this population. A systematic literature search identified studies of gestational or pregestational diabetes comparing use of insulin glargine with human NPH insulin, with at least 15 women in both arms. Data was extracted for maternal outcomes (weight at delivery, weight gain,...

OBJECTIVE Women with diabetes in pregnancy have high rates of pregnancy complications. Our aims were to explore trends in the incidence of diabetes in pregnancy and examine whether the risk of serious perinatal outcomes has changed. RESEARCH DESIGN AND METHODS We performed a population-based cohort study of 1,109,605 women who delivered in Ontario, Canada, between 1 April 1996 and 31 March 20...

Background Pregestational diabetes mellitus (PGDM) is associated with adverse pregnancy outcomes. Studies assessing interventions to improve maternal and infant outcomes have increased exponentially over recent years. Several in this field of are rare, making it difficult synthesise evidence. Objectives To collect reported studies treatment pregnant women PGDM. Search strategy CENTRAL, Web Scie...