this study aimed to compare the efficacy of mta and cem cement in class ii furcation defects in human mandibular molars.forty furcation defects were treated in 16 patients with chronic periodontitis. the clinical parameters of probing depth (pd), vertical and horizontal clinical attachment levels (vcal and hcal), open vertical and horizontal furcation depths (ovfd and ohfd), and gingival margin...

Mesenchymal stem cells (MSCs) have the ability to differentiate into neuronal like cells under appropriate culture condition. In this study, we investigated whether MSCs derived from human peripheral blood (PB-MSCs) can differentiate into neuronal like cells by synergic effect of the growth factors EGF, bFGF and Noggin. For this purpose, the expression of five neuronal markers (Nestin, &beta II...

in recent years, the cloning technology has remarkably developed iran, but unfortunately, the required legal framework has not been created to support and protect such developments yet. this legal gap may lead to abuse of scientific researches to obtain illegal benefits and to undermine the intellectual property rights of scientists and researchers. thus to prevent such consequences, the attemp...

stem cells are self-renewing and undifferentiated cell types that can be differentiate into functional cells. stem cells can be classified into two main types based on their source of origin: embryonic and adult stem cells. stem cells also classified based on the range of differentiation potentials into totipotent, pluripotent, multipotent, and unipotent. multipotent stem cells have the ability...

the human placenta has long been the subject of scientific interest due to the important roles which it performs during pregnancy in sustaining the fetus and maintaining fetomaternal tolerance. more recently, however, researchers have begun to investigate the possibility that the placenta’s utility may extend beyond fetal development to act as a source of cells with clinically relevant properti...

Although regeneration of tissues occurs in all adult tetrapods, the ability to regenerate complex structures such as limbs is limited to urodeles (newts and salamanders). Given that many of the biological processes and the signaling pathways that control these processes are highly conserved among all tetrapods, it is likely that humans have the potential to regenerate structures in the same way...

Regenerative medicine is the science of replacing engineering, regenerating human cells, tissues, or organs to restore establish normal function and has now reached its potential due ability deliver cell tissue constructs body thus providing therapeutic assistance innate healing responses. It further comprehends cellular molecular differences between non-regenerating tissues resulting in restor...

We have battled against disease since the beginning of time. As science and technology have evolved, so have the weapons in our antidisease arsenal improved. Indeed, in the last 50 years, the sheer volume of knowledge about human biology has doubled every 8 years. This means that the foundation on which the design and delivery of healthcare is built is 1,000 times stronger at the end of our liv...

Throughout their lifetime, an individual may sustain many injuries and recover spontaneously over a period of time, without even realizing the injury in the first place. Wound healing occurs due to a proliferation of stem cells capable of restoring the injured tissue. The ability of adult stem cells to repair tissue is dependent upon the intrinsic ability of tissues to proliferate. The amazing ...