Background: In order to select a better antibiotic choice for treatment of Pseudomonas aeruginosa infections, this study was conducted to determine the frequency of resistance to some antipseudomonal β-lactams in P. aeruginosa isolates from patients in Tehran, Iran. In addition, the relation between presence of genes known to be responsible for resist...

lepidoteran pests of sugar beet (beta vulgaris l.) cause a severe yield reduction in the most sugar beet growing areas of the world as well as in iran. due to limited genetic resources of resistance to insect pest and polygenic inhertance, improvement of pest resistance in beet by conventional breeding is a difficult task. biotechnological enhancement by introducing insect resistance genes such...

conclusions the trat gene and pai markers were highly prevalent among upec strains isolated from patients in kashan, iran; therefore these determinants could be used as targets for prophylactic interventions. also there was a high level of resistance against the antibiotics commonly used for urinary tract infection treatment. to reach better therapeutic outcomes, treatment regimens have to be m...

a study was conducted to identify ssr markers linked to leaf rust resistance genes lr24 and lr28 and to be used for marker-assisted selection (mas) to transfer both genes to a widely cultivated wheat variety mp 3299 under rainfed condition. f2 individuals of the cross mp 3299×nil pbw 343 were used for generating genotypic data employing closely linked scar markers s73719 and s421570 to lr24 and...

objective(s): p-glycoprotein (p-gp) is an efflux protein, the overexpression of which has been associated with multidrug resistance in various cancers. although sirna delivery to reverse p-gp expression may be promising for sensitizing of tumor cells to cytotoxic drugs, the therapeutic use of sirna requires effective carriers that can deliver sirna intracellularly with minimal toxicity on targe...

  Background and Objective: Methicillin resistance in Staphylococcus aureus is an increasingly important clinical problem. A chromosomal gene, mecA, mediates resistance to penicillinase-resistant penicillins such as methicillin and oxacillin in Staphylococcus aureus. We evaluated the validity of disk diffusion test by using oxacillin, methicillin an...

Introduction: The major resistance mechanisms of Pseudomonas aeruginosa to fluoroquinolones and carbapenems are associated with the mutations in the genes gyrA and oprD encoding type II topoisomerases (DNA gyrase) and OprD porin, respectively. Method: In this cross-sectional study, sixty five clinical samples were collected from patients hospitalized in Al-Zahra Hospital of Isfahan, Iran. Susce...

Nucleotide binding site leucine-rich repeats (NBS-LRR) accounting for the main disease resistance proteins play an important role in plant defense against pathogen attack. The current study aimed to identify new NBS-LRR gene members in native types of cucurbit species in Iran. Accordingly, DNAs of melon, cucumber and cantaloupe native types to Iran were identified using three primer pairs. PCR ...

objective: the rifampicin resistance and susceptibility of mycobacterium tuberculosis are caused by mutations in the 81-base pair region of the rpob gene encoding the b-subunit of rna polymerase. methods: isoniazid resistance of m. tuberculosis is related to mutations in inha , oxyr and ahpc genes which 30 to 90 percent of isoniazid resistance is occurred in 3015 codons of katg gene. the rpob a...