INTRODUCTION Over the last decade or so, no other subspecialty of medicine has seen such technological innovations, as interventional cardiology. These advances have revolutionized the management of coronary artery disease. From statin drugs to oral platelets inhibitors like clopidogrel and ticlopidine, intravenous platelet glycoprotein IIb/IIIa receptor blockers like Abciximab (Reo-Pro), Eptif...

BACKGROUND The primary mechanism of action of glycoprotein (GP) IIb/IIIa antagonists is inhibition of the final common pathway of platelet aggregation: fibrinogen binding to the GP IIb/IIIa complex. However, it has been reported that induction of fibrinogen binding and platelet aggregation is an intrinsic prothrombotic property of low-dose GP IIb/IIIa antagonists. These apparently paradoxical r...

Prospective, controlled, randomized study enrolled 100 patients with acute anterior STEMI eligible for primary PCI equally divided into 2 groups (group A received bolus intracoronary eptifibatide and group B received it intravenous) followed by 12h continuous IV infusion. Predictors of myocardial salvage in the form of TIMI flow grade III, myocardial blush grade 3, ST segment resolution and lef...

a new type of magnetically-recoverable catalyst was synthesized by the immobilization of h3pw12o40 on the surface of silica-encapsulated -fe2o3 nanoparticles. a series of novel 1,3,5-triaryl pyrazoline derivatives has been synthesized by the reaction of chalcone and phenylhydrazine in the presence of the -fe2o3@sio2-pw12nanoparticles,  in high yields. the structures of compounds obtained were...

backgrounds the degree of microleakage is one of the main criteria in evaluating the restorative materials such as glass ionomer (gi) restoratives, which are available in two forms: loose powder and liquid form to be hand-mixed or pre-proportioned in a capsule to be mixed mechanically. objectives this study was conducted to compare the microleakage of encapsulated gi restoratives with their han...