Introduction: Esophageal Squamous-Cell Carcinoma (SCC) is one of the most common malignancies in Iran. To reduce the incidence of esophageal SCC, it is important to recognize the controllable risk factors and prevent them. Celiac disease is widely known as a possible risk factor for esophageal SCC.  Thus, we decided to assess the frequency of celiac disease in esophageal SCC patients in North...

BACKGROUND Association between celiac disease and type 1 diabetes in adults is still somewhat unclear, and that between celiac disease and type 2 diabetes even less known. We studied these issues in a large cohort of adult celiac disease patients. METHODS The prevalence of type 1 and type 2 diabetes in 1358 celiac patients was compared with the population-based values. Furthermore, patients w...

OBJECTIVE This study examines the use of HLA typing for the diagnosis of celiac disease in a group of Australians with type 1 diabetes. RESEARCH DESIGN AND METHODS Subjects included 131 sequential patients with type 1 diabetes (mean age 17 years [range 10-37]), 77 patients with biopsy-proven celiac disease (mean age 52 years [range 12-84]), and 162 healthy control subjects (mean age 17 years ...

OBJECTIVE Earlier studies suggest that children with type 1 diabetes are more likely to have a subsequent diagnosis of celiac disease. However, research is sparse on the risk of subsequent type 1 diabetes in individuals with celiac disease. We sought to determine the risk of subsequent type 1 diabetes diagnosed before the age of 20 years in children and adolescents with celiac disease in a nati...

BACKGROUND Celiac disease is a multi-system disorder with manifestations that may result in psychiatric disorders. We assessed the prevalence of medication use to treat psychiatric disorders in celiac disease patients. METHODS We conducted a cross-sectional study of patients undergoing esophagogastroduodenoscopy over 9-years at a celiac disease referral center. We compared the prevalence of p...

aim : the aim of this study was to determine the prevalence of celiac disease in iranian patients suffering from chronic depression or schizophrenia. background : psychiatric disorders are common in untreated celiac disease. patients and methods : two hundred iranian inpatient men with in chronic phase of depressive disorders or schizophrenia, and 200 age-matched healthy male subjects were scre...

Celiac disease is an immune-mediated intestinal disorder that may be associated with other immunemediated extra-intestinal disorders, including immune-mediated endocrine diseases, such as autoimmune thyroiditis, most often with hypothyroidism. Other monoglandular autoimmune endocrine disorders may also occur, including autoimmune adrenal insufficiency (Addison’s disease). In celiac disease, cli...

Background & Aims: The aim of this study was to determine the yield of screening for celiac disease in children with failure to thrive and with or without chronic diarrhea. Methods: In this prospective study, 144 children aged 1-14 years and weighed below the fifth percentile with or without chronic diarrhea were studied during six months in 2010. Sample collection was done in the private offic...

background: single-nucleotide polymorphism (snp) rs2476601 within protein tyrosine phosphatase non-receptor type 22 gene (ptpn22) has been shown to be a risk factor for different autoimmune diseases. this study explored the association of 1858 c/t snp with rheumatoid arthritis (ra) and celiac disease (cd) in a region covering south-west of iran. methods: totally, 52 patients with cd, 120 patien...

background : an elevation in the mean percentages of the gamma delta t lymphocytes per total t cells in the epithelium of the small intestine has a diagnostic value for celiac disease.  this study aimed to measure the percentages of the peripheral blood gamma delta t lymphocytes in the adults' celiac disease and healthy controls. materials and methods: in this case-control study the absolute nu...