BACKGROUND AND OBJECTIVES The objective of this study was to describe the normal range of serum cystatin C and identify factors associated with variability in serum cystatin C contrasting with factors that are known to influence creatinine levels in the general US adolescent population. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Serum cystatin C and creatinine were measured in 719 particip...

BACKGROUND The aim of this study is to evaluate the association between acute serum creatinine changes in acute renal failure (ARF), before specialized treatment begins, and in-hospital mortality, recovery of renal function, and overall mortality at 6 months, on an equal degree of ARF severity, using the RIFLE criteria, and comorbid illnesses. METHODS Prospective cohort study of 1008 consecut...

background: thalassemia is one of the most common hereditary disorders and beta-thalassemia major is its severe form. the present study is concerned with the analysis of liver function, thyroid function and estimation of critical serum ions as well as hematological characteristics in beta-thalassemia patients and controls. subjects and methods: the study included 54 patients with beta-thalassem...

We evaluated the outcomes of percutaneous nephrolithotomy in patients with chronic renal insufficiency. A total of 60 patients with a creatinine level greater than 1.5 mg/dL who underwent PCNL were included. Serum creatinine level, as a kidney function index, was assessed before and after the operation. The mean calculus size was 31.13 ± 9.38 mm. The mean pre-operative and 2-week postoperative ...

introduction: several mechanisms were introduced as causes of serum creatinine phosphokinase (cpk) raise in intoxicated patients. this study aimed to assess the relationship between serum cpk level in the first 24 hours and baseline characteristics as well as outcomes of these patients. methods: this one year retrospective cross-sectional study was conducted on all intoxicated patients, who wer...

BACKGROUND Amphotericin B is a widely used broad-spectrum antifungal agent, despite being associated with significant adverse events, including nephrotoxicity. METHODS The present prospective study collected data on outcomes for 418 adult patients treated consecutively with polyenes in hematology and oncology wards in 20 hospitals in Europe. RESULTS Patients initially received amphotericin ...

migraine is one of the common varieties of headache. it involves 4 to 6 percent of men and 13 to 16 percent of women under 30 years in more than 80% of cases. some studies have shown that in 50% of patients serum magnesium level decreases during attacks of headache and using magnesium tablets and intravenous magnesium sulfate is more effective for treatment of migraine attack, than placebo. thi...

Cystatin C is a 13 KD basic protein that is a member of the cystatin superfamily of cysteine protease inhibitors. The cystatin C gene seems to be a house keeping gene, which is compatible with a stable production rate of cystatin C by most cells. This protein is freely filtered through the glomerulus and almost completely reabsorbed and catabolized by proximal tubular cells. Because of the...