Introduction: The choice of optimal radionuclides for radioimmunotherapy depends on several factors, especially the radionuclide and antibody. The dosimetric characteristics of a non-internalizing and an internalizing monoclonal antibody (MAb) labeled with beta emitting radionuclides were investigated. Methods: Using Geant4-DNA Monte Carlo simulation, we ...

OBJECTIVES This study compares the behavioral profile of children with fetal alcohol spectrum disorder (FASD) who were diagnosed using the Canadian Guidelines with children with prenatal alcohol exposure who did not meet criteria for a FASD diagnosis. METHODS AND PROCEDURES To accomplish this, we used caregiver and teacher questionnaires evaluating different aspects of behavior. Investigated ...

This Special Issue of Development and Psychopathology is devoted to a multilevel developmental understanding of internalizing psychopathology. In an earlier Special Issue (Burnette & Cicchetti, 2012), contributors focused upon a multilevel developmental perspective of externalizing pathology. Internalizing and externalizing expressions of dysfunction comprise one of the most widely agreed upon ...

This study used structural equation modeling to examine the relationships between emotion dysregulation, internalizing symptoms, nonsuicidal self-injury (NSSI), and suicide. One hundred forty-eight undergraduates completed a brief structured interview and self-report measures of emotion dysregulation, internalizing symptoms, and NSSI and suicidal behaviors. Results indicated a significant indir...

The aim of this investigation was to map factors that predicted internalizing, externalizing, social, and total behavioral problems in immigrant Latino adolescents. Interviews were conducted with 100 foreign-born Latino adolescents. Multiple regression analyses revealed two risk factors, perceived discrimination and parent-adolescent conflict, which were significant predictors of adolescent int...

Background/Aim. Nonsuicidal self-injury (NSSI) among adolescents is recognized as a significant public health concern. Adolescents with mental problems are at an especially high risk of NSSI. The aim the study was to assess sociodemographic and clinical characteristics patients NSSI features NSSI, well impact emotional reactivity internalizing/externalizing on them. Methods. observational inclu...

The current investigation examined if changes in youth internalizing problems as a result of a family group cognitive behavioral (FGCB) preventive intervention for families with a parent with a history of depression had a cascade effect on youth social problems over 24 months and the bidirectional nature of these effects. One hundred eighty families with a parent with a history of major depress...