background: patients with spinal cord injury (sci) have a lower health related quality of life (hrqol) compared to both healthy controls and the normal population. the aim of this study was to compare hrqol between two groups of veteran and non-veteran sci patients. methods : all male paraplegic non-veterans who had sustained complete sci before 1988 and were residents of tehran province (iran)...

results the results showed that bbb test showed an improvement in the cr, while the quantitative analysis showed that the improvement rate was higher in the rats treated with cnl than those treated with bmscs only or the untreated animals, similar results were noticed in the improvement index. immunohistochemical analysis of the tissue section prepared from the cr showed that the transplanted c...

Spinal cord injury (SCI) is currently incurable since treatments applied to clinic are limited to minimizing secondary complications and the mechanisms of injury-induced spinal cord damage are poorly understood. Zbtb38, also called CIBZ, is highly expressed in spinal cord and it functions as a negative regulator in SCI-induced apoptosis. We show here that Zbtb38 is downregulated under endoplasm...

INTRODUCTION Spinal cord injuries (SCIs) in football are rare but catastrophic events. The SCI incidence rate in the United States for high school, college, and professional football has been estimated as 0.52, 1.55, and 14 per 100,000 participants, respectively [1]. These injuries are very significant given the enormous economic and societal costs and the vastly diminished quality of life of t...

BACKGROUND Spinal cord injury (SCI) has a serious lifetime impact as well as obvious social and economic effects for both patients and society. The aim of this study was to collect recent information and analyze changes in the epidemiology of traumatic spinal injuries. METHODS Data included traumatic SCI (TSCI) patients admitted to the emergency department of Haydarpaşa Numune Training and Re...

OBJECT Stem cell therapy has been shown to have considerable therapeutic potential for spinal cord injuries (SCIs); however, most experiments in animals have been performed by injecting cells directly into the injured parenchyma. This invasive technique compromises the injured spinal cord, although it delivers cells into the hostile environment of the acutely injured cord. In this study, the au...

Objective(s): Recent studies revealed that microRNAs (miRNAs) may play crucial roles in the responses and pathologic processes of spinal cord injury (SCI). This study aimed to investigate the effect and the molecular basis of miR-103 on LPS-induced injuries in PC12 cells in vitro and SCI rats in vivo. Materials and Methods: PC12 cells were exposed to LPS to induce cell injuries to mimic the in ...

introduction: male infertility frequently occures after spinal cord injury (sci). however little in known about the acute effect of sci on male reproductive function. this study examined the spermatogenic changes during acute phase of sci. material and metods: in experimental groups sci was produced in male rats by t9 laminectomy and spinal cord transsection (n=23, age=70 days). control groups ...

abstract   objective: to evaluate and review our experience with pediatric spinal injuries and factors affecting outcome, the authors conducted a retrospective clinical study of 43 cases (32 boys, 11 girls) of pediatric spine injuries treated during four years (january 1999 to december 2003).   methods: forty-three children with spinal injuries were studied retrospectively over four years and w...