The harmful effects of 14 Chemotherapeutic drugs on spermatogenesis in the mouse have been evaluated by studies of testicular cell killing and morphological and genetic damage produced. Male mice were given drugs as single injections at various doses up to the toxic levels. Prednisone and 6-mercaptopurine produced little or no cytotoxicity. All other drugs tested killed differentiated spermatog...

Investigations with the melphalan-resistant human rhabdomyosarcoma xenograft TE-671 MR were carried out to identify patterns of cross-resistance and collateral sensitivity and to define the mechanism(s) mediating melphalan resistance. TE-671 MR was cross-resistant to thio-TEPA, mitomycin, vincristine, and cisplatin, and partially resistant to chlorambucil and cyclophosphamide. TE-671 MR and the...

Tetraethylenepentamine (TEPA)-based mesoporous MCM-41 is used as the adsorbent to determine the CO2 desorption kinetics of amine-modified materials after adsorption. The experimental data of CO2 desorption as a function of time are derived by zero-length column at different temperatures (35, 50, and 70 ◦C) and analyzed by Avrami’s fractional-order kinetic model. A new method is used to distingu...

PURPOSE Relationships between toxicity and pharmacokinetics have been shown for cyclophosphamide, thiotepa, and carboplatin (CTC) in high-dose chemotherapy. We prospectively evaluated whether variability in exposure to CTC and their activated metabolites can be decreased with pharmacokinetically guided dose administration and evaluated its clinical effect. EXPERIMENTAL DESIGN Patients receive...

Previous studies have demonstrated that a, semisynthetic diet containing 12 per cent casein is deficient in sulfur amino acids for the growth of tissues in rats (1), supplementation with 0.7 per cent DL-methionine increasing the growth opti mally. A transplanted sarcoma was found to de velop most rapidly in rats fed this sulfur amino acid-deficient diet. Supplementing with 0.7 per cent methioni...

İklim değişikliğinin en önemli sebeplerinden birisi olan karbondioksit (CO2) emisyonlarının birincil kaynağı, enerji üretiminde fosil yakıtların kullanılmasıdır. Yanma sonrası oluşan CO2 emisyonlarını azaltmak için, adsorpsiyon ve özellikle karbon bazlı adsorbanların kullanımının oldukça etkili olduğu kanıtlanmıştır. Bu amaçla kullanılan nanotüplerin, kapasitesini artırmak için farklı modifikas...

Aerosol water content (AWC) significantly affects secondary aerosol formation and atmospheric visibility. Most ambient AWC values are obtained from models because the direct measurement is challenging. In this study, sequential aerosol-water system (SAWMS) was applied to measure at Xiaogang (XG) air-quality monitoring site of Taiwan Environmental Protection Administration (TEPA), located in an ...

This research focuses on Johan Galtung’s theory of the culture peace. Based his thoughts, problems in this study are: 1). What is Galtung's concept a peace? 2). The methods and approaches used by Galtung dealing with conflicts so as to get 3). Where relevance thoughts cultural conditions peace Indonesia? His findings, 's without war physical violence focus preventing violent wars between within...

BACKGROUND We have previously demonstrated that the copper chelator tetraethylenepentamine (TEPA) enables preferential expansion of early hematopoietic progenitor cells (CD34+CD38-, CD34+CD38-Lin-) in human umbilical cord blood (CB)-derived CD34+ cell cultures. This study extends our previous findings that copper chelation can modulate the balance between self-renewal and differentiation of hem...

This work deals with the development of non-isocyanate polyurethane (NIPU) composites an aniline oligomer, viz., tetraniline (TANI) for corrosion-resistant coatings. Firstly, epoxidizedsoyabean oil was converted to carbonated by inserting CO2 under high temperature and pressure into epoxy ring. Then, varying weights oligoaniline—0.5, 1, 2 4 wt % (based on weight CSBO)—were added CSBO cured tetr...