To measure the causal impact of broker recommendations on their clients portfolios, we exploit time-series variation in access to brokers in a defined contribution retirement plan. When brokers are available, we predict demand for brokers using administrative data on plan participants. The observed correlations with age, income, and educational attainment suggest that brokers are chosen by part...

Introduction: The induction of human umbilical cord-derived mesenchymal stem cells (HUC-MSCs) toward dopaminergic neurons is a major challenge in tissue engineering and experimental and clinical treatments of various neurodegenerative diseases, including Parkinson disease. This study aims to differentiate HUC-MSCs into dopaminergic neuron-like cells. Methods: Following the isolation and charac...

Short RNAs derived from the cleavage of tRNA molecules are observed in most organisms. Their occurrence seems to be induced by stress conditions, but still little is known about their biogenesis and functions. We find that the recovery of tRNA fragments depends on the RNA isolation method. Using an optimized RNA extraction protocol and northern blot hybridization technique, we show that the tRN...

Introduction: The litterfall production, foliar nutrient dynamics and decomposition are essential to maintain cycling, soil fertility, carbon regulation in terrestrial ecosystems. With several studies addressing the variation of these processes, their tropical dry forests (TDFs) remain unclear, due its complex interaction biotic abiotic factors. Objective: To evaluate litterfall, potential retu...

High-throughput sequencing has the potential to answer many of the big questions in biology and medicine. It can be used to determine the ancestry of species, to chart complex ecosystems and to understand and diagnose disease. However, going from raw sequencing data to biological or medical insights is far from trivial. A key challenge is that these methods cannot read the input sequences in th...

vacuolar h+-translocation pyrophosphatase (v-ppase) and na+/h+ antiporter (v-na+/h+) are important transporters in plant cells and have essential roles against abiotic stresses. in this study, the effects of salt stress were surveyed on the transcription of v-ppase pump and na+/h+ antiporter genes at early times of nacl treatment in roots of halophytic grass leptochloa fusca through the real ti...

Citation: Tian X, Ma J, Wang T, Tian J, Zhang Y, Mao L, Xu H and Wang S (2018) Long Non-Coding RNA HOXA Transcript Antisense RNA MyeloidSpecific 1–HOXA1 Axis Downregulates the Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in Lung Cancer. Front. Immunol. 9:473. doi: 10.3389/fimmu.2018.00473 long non-coding rna hOXa Transcript antisense rna Myeloid-specific 1–hOXa1 axis Downregul...

Viral transgenes designed to provide resistance to specific plant viruses frequently consist of the coat protein gene and a contiguous 3' untranslated region (3'UTR) of viral origin. In many RNA viruses the viral 3'UTR establishes a recognition and initiation site for viral RNA replication. Thus the transgenic transcript may contain a functional virus replication site. Experiments were designed...