Several software programs have been designed for outcome prediction of orthodontic and surgical treatments. This study aimed to review the accuracy and characteristics of cephalometric software programs for outcome prediction of orthognathic surgeries. This study reviewed studies that compared cephalometric software programs in terms of accuracy and characteristics for outcome prediction of o...

OBJECTIVES Radiofrequency facet joint denervation procedures have been common practice for 2 decades in treatment of chronic low back pain. We designed this multicenter, randomized, double-blind, sham treatment controlled trial to determine the efficacy of radiofrequency facet joint denervation, as it is routinely performed. METHODS Inclusion criteria were low back pain, duration more than 6 ...

BACKGROUND Internet-based cognitive behavioral therapy (ICBT) is a form of guided self-help that has been found to be effective for addressing several problems. The target for this type of therapy is usually restricted to one specific disorder. Tailoring the treatment widens the scope of ICBT in that it can address comorbid conditions directly. OBJECTIVES The working, or therapeutic, alliance...

Measuring Treatment Effect in Acute Stroke Trials To the Editor: We read with interest Bruno et al’s analysis of National Institutes of Health Stroke Scale (NIHSS) score in the trial of Org 10172 in acute stroke treatment (TOAST). They found the dichotomous variable, NIHSS score 2 at 3 months, to be associated with “very favorable outcome” at 3 months, defined as both Glasgow Outcome Scale of 1...

Outcome measurements are essential to monitor the clinical course or treatment response of peripheral neuropathy. Even though there no designated standard scale for neuropathy currently, several scales were validated use outcome based on many researches. Here, we reviewed commonly used and fulfilled clinimetric properties in neuropathy, especially focusing inflammatory (Guillain-Barré syndrome,...

OBJECTIVES To review the outcome measures commonly used in phase III treatment trials of relapsing-remitting multiple sclerosis and to introduce a method of data analysis which is clinically appropriate for the often reversible disability in this type of multiple sclerosis. METHODS The conventional end point measures for disability change are inadequate and potentially misleading. Those using...

Background Evaluation of treatment programs in addiction field is a prerequisite to improve the quality of care. This study aimed to investigate the effectiveness of Therapeutic Community (TC) program in Iran.   Methods Individuals who had voluntarily enrolled in the TC center within a period of seven years, from early 2005 to late 2011, entered the study. Those who successfully completed the 1...

Background/Objective: The aim of the present preliminary study was to assess the demographic, clinical, paraclinical, microbiological, echocardiographic, and therapeutic profile as well as in-hospital outcome of patients with infective endocarditis at a referral center for various infectious diseases in Iran.Methods: Required demographic, clinical, plausible complications and paraclinical data ...