Aim: We assessed the safety and efficacy of three different local anesthesia methods (pudendal nerve blockade, tenoxicam suppository and rectal lidocaine gel) before transrectal ultrasound (TRUS)-guided biopsy of the prostate in this study. Materials and Methods: In our prospective and controlled study, 136 consecutive patients were randomized into four groups: men in group 1 (n=41) received no...

Purpose: Prolong labour contributes to increased perinatal and maternal morbidity. Inhibitory impulses in the form of spasm often impair the dilatation of cervix and prolong the duration of labour. This study was undertaken to compare the effect of intramuscular Valathemate bromide [Epidosin] and Hyoscine N Butylbromide [Buscopan] rectal suppository on duration of labour and rate of cervical di...

OBJECTIVE A large proportion of vulvovaginal candidiasis (VVC) in diabetes is due to non-albicans Candida species such as C. glabrata and C. tropicalis. Observational studies indicate that diabetic patients with C. glabrata VVC respond poorly to azole drugs. We evaluated the response to oral fluconazole and boric acid vaginal suppositories in diabetic patients with VVC. RESEARCH DESIGN AND ME...

The aim of this research was to study and compare the mechanism of action of interleukin (IL)-8, IL-1beta dehydroepiandrosterone sulphate (DHEA-S) and prostaglandin (PG)E2 on the cervix. Five equal groups of pregnant rabbits (n = 45) were tested by either placebo or tested drugs in the form of vaginal suppositories once daily for 3 days. The suppositories contained human recombinant IL-8 (100 n...

Suppository diclofenac instead of intravenous meperidine for postoperative management

background: post episiotomy pain affects a large number of women after the delivery. the common method for pain relief is using oral non-steroidal anti-inflammatory drugs. considering the side effects of these medicines, the aim of present study was to compare the effects of indomethacin suppository and mefenamic acid capsule on post episiotomy pain. methods: in a clinical trial study, sixty wo...

BACKGROUND Chest tube removal is a painful procedure. The goal of this study was to evaluate the effect of cold application in combination with Indomethacin suppository on chest tube removal pain in patients undergoing open heart surgery. MATERIALS AND METHODS This single-blind, double-group clinical trial was performed on 66 patients aged 18-68 years with the chest tube in pleural space. The...

Plantago major has been used widely since ancient times, to manage a wide range of diseases including constipation, coughs and wounds. The aim of this study is to review the traditional application, botanical characterization, pharmacological activities, phytochemistry effects and toxicity of Plantago major. In this review study, medicinal properties of Plantago major are collected from credibl...