Voltage-sensitive phosphatases (VSPs) are proteins that directly couple changes in membrane electrical potential to inositol lipid phosphatase activity. VSPs thus couple two signaling pathways that are critical for cellular functioning. Although a number of nonmammalian VSPs have been characterized biophysically, mammalian VSPs are less well understood at both the physiological and biophysical ...

Recently, there is a growing interest in seismic qualification of ridges, buildings and mechanical equipment worldwide due to increase of accidents caused by earthquake. Severe earthquake can bring serious problems in the wind turbines and eventually lead to an interruption to their electric power supply. To overcome and prevent these undesirable problems, structural design optimization of a sm...

To prove a direct relationship between the quasi-static electric field disturbances and seismic activity is a difficult, but actual task of the modern ionosphere physics. This paper presents new results on the processing and analysis of the quasi-static electric field in the upper ionosphere (h=800–900 km) observed from the satellite INTERCOSMOS-BULGARIA-1300 over earthquakes’ source regions (s...

Giardia lamblia infections are associated with antigenic variation of the parasite, which is generated by a continuous change of the variant-specific surface proteins (VSPs). Many investigations on the process of antigenic variation were based on the use of G. lamblia clone GS/M-83-H7, which expresses VSP H7 as its major surface antigen. In the present study, mice were infected with the aforeme...

Seismic data are recorded and commonly interpreted in vertical two-way time; well logs, measured in depth, must be tied to seismic using a time-depth curve. However, well ties contain a large amount of uncertainty due to errors in the generation of synthetic seismograms and manual matching of synthetic seismograms to seismic traces. Using dynamic time warping, a fast algorithm that optimally al...

We calculate the vertical mass discharge rate from Mount St. Helens for the first few minutes of the May 18, 1980 cataclysmic eruption using a new method based on seismic constraints. The observed seismic waves indicate that the seismic source is a series of single forces. We model these forces as thrusts due to a combination of the momentum flux of the erupted products and the pressure of the ...

In this paper we present a study of feasibility by using Cassino Parallel Manipulator (CaPaMan) as an earthquake simulator. We propose a suitable formulation to simulate the frequency, amplitude and acceleration magnitude of seismic motion by means of the movable platform motion by giving a suitable input motion. In this paper we have reported numerical simulations that simulate the three princ...

Failure of the quay walls due to earthquakes results in severe economic loss. Because of hazards threatening such inexpensive nodes of national and international transportation networks, seismic design of quay walls is still an evolving topic in marine structural engineering. This study investigates the sensitivity of the gravity-type quay wall stability respect to uncertain soil and seismic pr...

Sayers and Kachanov (1991) defined crack-influence parameters that are shown to be directly related to Thomsen (1986) weak-anisotropy seismic parameters for fractured reservoirs when the crack/fracture density is small enough. These results are then applied to the problem of seismic wave propagation in polar (i.e., non-isotropic) reservoirs having HTI seismic wave symmetry due to the presence o...