Effects of a new shape-memory alloy interspinous process device on pressure distribution of the intervertebral disc and zygapophyseal joints in vitroos4_63 38..45 *Qing-qiang Yao MD, *Sheng-nai Zheng MD, Li Cheng MD, Peng Yuan MD, Dong-sheng Zhang MD, Xiang-wen Liao MD, Yan Xu MD, Li-ming Wang MD Department of Orthopaedic Surgery, Nanjing First Hospital Affiliated to Nanjing Medical University,...

Hypertension-induced left ventricular hypertrophy is the most important risk factor for heart failure. This study aimed at investigating the effects of monoterpenoid phenol, carvacrol, on myocardial hypertrophy using both in-vivo and in-vitro models. Male Wistar rats were divided into the control (Ctl), un-treated hypertrophy (H), and carvacrol-treated hypertrophy gro...

The articulations of the spinal motion segment, the intervertebral disk, and the zygapophyseal joints, inevitably undergo age-related changes. This article focuses on the intervertebral disk, specifically when fissures sufficiently weaken the posterior annulus so as to allow herniation of nuclear material into the outer annular structure as a contained protrusion or breach the annulus and pass ...

Although lumbar instability is considered to be responsible for the majority of chronic or recurrent backaches, the word ‘instability’ is still poorly defined. A number of different definitions exist, but as yet there are no clear and validated clinical features by which instability might be diagnosed. It is also not clear how instability as such might set up pain and disability. It is generall...

Hypertension-induced left ventricular hypertrophy is the most important risk factor for heart failure. This study aimed at investigating the effects of monoterpenoid phenol, carvacrol, on myocardial hypertrophy using both in-vivo and in-vitro models. Male Wistar rats were divided into the control (Ctl), un-treated hypertrophy (H), and carvacrol-treated hypertrophy gro...

Osteoarthritis (OA) is the most common degenerative joint disease. The aetiology of OA is multifactorial, including joint injury, obesity, ageing and heredity. Inactivation of transforming growth factor beta (TGF-β) or its downstream molecules may be an important signalling event contributing to OA pathogenesis because mutations of Smad3, a central molecule in TGF-β signalling, have been found ...

Pigmented villonodular synovitis (PVNS) is a proliferative benign lesion originating from the synovium and commonly affects large joints of the extremities. PVNS can arise from any synovium in the whole body and rarely affects the zygapophyseal joints of the spine. Spinal PVNS is diagnosed mostly after resection of the mass. In our case we present a 22-year-old male patient showing progressive ...

BACKGROUND Graft hypertrophy is the most common complication of periosteal autologous chondrocyte implantation (p-ACI). PURPOSE The aim of this prospective study was to analyze the development, the incidence rate, and the persistence of graft hypertrophy after matrix-based autologous chondrocyte implantation (mb-ACI) in the knee joint within a 2-year postoperative course. STUDY DESIGN Case ...

Rheumatoid arthritis (RA) is the rheumatism mainly manifested as disabling joint disease and mainly involves hands, wrists, feet and other small joints. Recurrent arthritis attacks, synovial cell hypertrophy and hyperplasia and bone and cartilage damages eventually lead to joint dysfunction and other complications, and there is no cure. Quercetin (QU) is a kind of natural flavonoids, with lipid...