Subtilisin from the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 is a member of the subtilisin family. T. kodakaraensis subtilisin in a proform (T. kodakaraensis pro-subtilisin), as well as its propeptide (T. kodakaraensis propeptide) and mature domain (T. kodakaraensis mat-subtilisin), were independently overproduced in E. coli, purified, and biochemically characterized. T. kodak...

Individuals deficient in hepatic methionine adenosyltransferase (MAT) activity (MAT I/III deficiency) have been demonstrated to contain mutations in the gene (MATA1) that encodes the major hepatic forms, MAT I and III. MAT I/III deficiency is characterized by isolated persistent hypermethioninemia and, in some cases, unusual breath odor. Most individuals with isolated hypermethioninemia have be...

سابقه و هدف: ورود گونه­­ های ماهی مهاجم دراکوسیستم ­های آبی، سبب بروز انواع اثرات منفی اکولوژیکی اقتصادی-اجتماعی می ­­شود. اولین گام در تجزیه تحلیل مخاطرات ناشی از گونه­ غیر­بومی، شناسایی خطر است بر این اساس ابزارهای متعددی برای ارزیابی خطرات تهاجمی غیربومی به منظور پشتیبانی تصمیم گیرندگان گونه ­­ها ایجاد شده است. هدف پژوهش قدرت تیلاپیای شکم قرمز (Coptodon zillii) حوضه آبریز تالاب شادگان (حوضه‌...

BACKGROUND Meniscal tears are common knee injuries. Meniscal allograft transplantation (MAT) has been advocated to alleviate symptoms and delay osteoarthritis (OA) after meniscectomy. We investigated (1) the long-term outcome of MAT as a treatment of symptomatic meniscectomy, (2) most important factors affecting survivorship and (3) OA progression. METHODS From 1989 till 2013, 329 MAT were pe...

This paper presents a real time force sensing instrument that is designed for human gait analysis purposes. This instrument mainly consists of three main elements: the force sensing mat, signal conditioning and switching circuit and data acquisition device. In order to control and to process the incoming signals from the force sensing mat, Force-Logger and Force-Reloader program are developed u...

Over recent years, appreciation for the critical role of the meniscus in joint biomechanics has led to an emphasis on meniscal preservation. Meniscal allograft transplant (MAT) is a promising biological solution for the symptomatic young patient with a meniscus-deficient knee that has not developed advanced osteoarthritis. As surgical techniques are refined and outcomes continue to improve, it ...