La implantación del notariado público en el reino de Murcia es un interesante ejemplo modelo rápido establecimiento oficio ex novo, propio los territorios recién conquistados la Península Ibérica durante siglo XIII, cual fue estudiado para casos Sevilla, Córdoba, Valencia y Mallorca. Mediante análisis legislación documentos notariales conservados, pretendemos analizar paralelismos las divergenc...

BACKGROUND Patient attrition has been a challenge in managing HIV programs in resource-limited settings. AIM This study reviews the predictors of loss to follow-up (LTFU) in our hospital and suggests the best practices for dealing with the issue. SUBJECTS AND METHODS A 5-year retrospective cohort study of 1256 HIV-infected patients. Baseline CD4 counts, age, gender, year of enrolment, and a...

Metronidazole is used to treat trichomoniasis, bacterial vaginosis, and other diseases. There are controversy aspects about its teratogenicity. A teratogenic agent can alter morphology or subsequent function of the fetus. The aim of this study was to examine an alternative method for the recognition of the mechanism or the bimolecular potential changes in mice fetus caused by Metronidazole usin...

BACKGROUND The translation of Web-based physical activity intervention research into the real world is lacking and becoming increasingly important. OBJECTIVE To compare usage and effectiveness, in real-world settings, of a traditional Web 1.0 Web-based physical activity intervention, providing limited interactivity, to a Web 2.0 Web-based physical activity intervention that includes interacti...

Ligneous membranitis (LM) is a rare chronic inflammatory condition of the mucous membranes associated with plasminogen (encoded by PLG) deficiency in affected humans and dogs. In human, the condition is genetic in nature with numerous mutations and polymorphisms in PLG identified in affected individuals and related family members. The condition is uncommonly reported in dogs and, to date, no ge...