Defective binding of apolipoprotein E (apoE) to heparan sulfate proteoglycans (HSPGs) is associated with increased risk of atherosclerosis due to inefficient clearance of lipoprotein remnants by the liver. The interaction of apoE with HSPGs has also been implicated in the pathogenesis of Alzheimer's disease and may play a role in neuronal repair. To identify which residues in the heparin-bindin...

In this work we study the effect of some electrical prosperities on synthetic rubber reinforced with carbon black diluted in heptanes with concentrations from 0.2% gm/mole to 2.0% gm/ mole in temperatures range (100, 150, 200, 250, 300) C associated with amount weight of black carbon 5wt% added to the diluted rubber. The results of electrical properties measurement of Buna rubber reinforced wit...

To identify residues and segments in the central region of apolipoprotein A-I (apoA-I) that are important for the protein structure and stability, we studied the effects of four double charge ablations, D102A/D103A, E110A/E111A, R116V/K118A, and R160V/H162A, and two deletion mutations, Delta(61-78) and Delta(121-142), on the conformation and stability of apoA-I in the lipid-free state and in re...

BaP1 is a 22.7-kD P-I-type zinc-dependent metalloproteinase isolated from the venom of the snake Bothrops asper, a medically relevant species in Central America. This enzyme exerts multiple tissue-damaging activities, including hemorrhage, myonecrosis, dermonecrosis, blistering, and edema. BaP1 is a single chain of 202 amino acids that shows highest sequence identity with metalloproteinases iso...

سابقه و هدف: در سال­ های اخیر روند رو به افزایش تخریب منابع آب، خاک محیط زیست اثر کاربرد بی رویه مواد شیمیایی موجب ترغیب پژوهشگران کشاورزی ارگانیک سال ­های شده است. با وجود همه اثرات مثبتی که ارتباط مصرف آلی بر روی ویژگی­ فیزیکی مطرح است، هنوز این رابطه نگرانی­ زیادی از نظر مسائل زیست­ محیطی، سلامت دارد. بسته منبع، اغلب دارای مقادیر نسبتا عناصر سنگین می باشند؛ بنابراین اندازه گیری دقیق میزان فل...

In this paper, utilization of clustering algorithms for data fusion in decision level is proposed. The results of automatic isolated word recognition, which are derived from speech spectrograph and Linear Predictive Coding (LPC) analysis, are combined with each other by using fuzzy clustering algorithms, especially fuzzy k-means and fuzzy vector quantization. Experimental results show that the ...

We study Tamagawa numbers of elliptic curves with torsion Z/2Z?Z/14Z over cubic fields and an n-isogeny Q, for n?{6,8,10,12,14,16,17,18,19,37,43,67,163}. Bruin Najman [3] proved that every curve a field is base change defined Q. find Q are always divisible by 142, each factor 14 coming from rational prime split multiplicative reduction type I14k, one which p=2. The only exception the 1922.e2, c...

We report the first direct measurement of differential transfer cross sections using a Recoil Mass Spectrometer. Absolute 1p- and 2p-stripping at $$\theta _\mathrm {c.m.}=180^\circ $$ have been determined for system $$^{16}$$ O+ $$^{142}$$ Ce by detecting heavier target-like ions focal plane Heavy Ion Reaction Analyzer. Focal spectra compared with results semi-microscopic Monte-Carlo simulation...