PLM is universally recognized as a valid strategy to reduce time to market, increase process efficiency and reduce lifecycle cost. Despite the importance for industry to prove these emphasized competitive advantages, PLM achievable benefits still remain intangible. Their measurement is particularly difficult in case of networked enterprises where each of them is characterized by different organ...

OBJECTIVES To detect changes in the collagen fibril network in articular cartilage in a canine experimental model of early osteoarthritis (OA) using microscopic magnetic resonance imaging (microMRI) and polarised light microscopy (PLM). METHODS Eighteen specimens from three pairs of the medial tibia of an anterior cruciate ligament transection canine model were subjected to microMRI and PLM s...

This paper presents a knowledge management experiment carried out in an industrial company. Our research concerns the development of a knowledge engineering module integrated in a PLM system which is based on a multi-domain scheme (project, product, process and use) taking into consideration several viewpoints (structural, functional, dynamic, etc.). This PLM system enables us to capture techni...

Companies that collaborate within the product development processes need to implement an effective management of their collaborative activities. Despite the implementation of a PLM system, the collaborative activities are not efficient as it might be expected. This paper presents an analysis of the problems related to the collaborative work using a PLM system. From this analysis, we propose an ...

Betriebliche Informationssysteme zum Produktlebenszyklusmanagement (PLM) dienen in den Unternehmen der Integration von technischer und betriebswirtschaftlicher Informationsverarbeitung. Ihnen kommt eine besondere Bedeutung für die produktbezogene Kostenschätzung im Angebotsengineering und tendenziell für das Lebenszykluskostenmanagement zu. Im vorliegenden Beitrag wird diese zentrale Rolle von ...

PURPOSE In a collaborative effort between the Missouri Department of Health, Area Agencies on Aging (AAA), Alzheimer Association, and academic researchers, we tested whether early dementia detection and comprehensive care consultations would improve health outcomes in care receivers (CRs) and their family caregivers (FCGs), therefore addressing an important public health concern. PARTICIPANTS...

Passive leg movement (PLM), an assessment of predominantly nitric oxide-dependent vasodilation, is decreased with age and cannot be augmented by posture-induced increases in femoral perfusion pressure in older men. However, this novel method of assessing vascular function has yet to be used to evaluate alterations in nitric oxide-dependent vasodilation with age in females. PLM was performed in ...

Periodic Limb Movements (PLMs) are episodic, involuntary movements caused by fairly specific muscle contractions that occur during sleep and can be scored during nocturnal polysomnography (NPSG). Because leg movements (LM) may be accompanied by an arousal or sleep fragmentation, a high PLM index (i.e. average number of PLMs per hour) may have an effect on an individual's overall health and well...

The past years have seen growing investments in the area of product lifecycle management (PLM) by the automotive sector. Due to its complex development cycle, the automotive OEM has begun to adopt the supplier integration into its product development process. To respond to this new trend, the PLM system needs to evolve to support the collaboration and partnership management between the automoti...