نتایج جستجو برای: 1d
تعداد نتایج: 21549 فیلتر نتایج به سال:
The 5-hydroxytryptamine (5-HT) 1D/1B receptors have gained particular interest as potential targets for treatment of migraine and depression. G-protein coupling and other intrinsic properties of the human 5-HT(1D) receptor were studied using a baculovirus-based expression system in Sf9 cells. Coexpression of the human 5-HT(1D) receptor with Galpha(i1), alpha(i2), alpha(i3), or Galpha(o)-protein...
OBJECTIVE To provide a management approach for adults with calcium channel blocker poisoning. DATA SOURCES, STUDY SELECTION, AND DATA EXTRACTION Following the Appraisal of Guidelines for Research & Evaluation II instrument, initial voting statements were constructed based on summaries outlining the evidence, risks, and benefits. DATA SYNTHESIS We recommend 1) for asymptomatic patients, obse...
We compared DNA replication, protein biosynthesis, and mitogen-activated protein kinase (MAPK) activity in Rat 1 fibroblasts stably expressing either the 1B-adrenergic receptor (AR) or 1D-AR subtypes. Activation of both the 1B-AR and 1D-AR inhibited DNA synthesis (as assessed by [H]thymidine incorporation). In contrast, both receptors stimulated protein biosynthesis (as measured by [S]methionin...
normal 0 false false false en-us x-none fa background: the angular dependency of response for tld cards may cause deviation from its true value on the results of environmental dosimetry, since tlds may be exposed to radiation at different angles of incidence from the surrounding area. objective: a 3d setting of tld cards has been calibrated isotropically in a standard radiation field to eval...
A fast (100 MHz) 1D coded aperture visible light camera has been developed as a prototype for imaging plasma experiments in the EUV/X-ray bands. The system uses printed patterns on transparency sheets as the masked aperture and an 80 channel photodiode array (9 V reverse bias) as the detector. In the low signal limit, the system has demonstrated 40-fold increase in throughput and a signal-to-no...
Metronomic chemotherapy is based on administration of anticancer agents at low-doses at close regular intervals with no prolonged breaks, and aims to inhibit vascular endothelial cells as well as tumor cells. Recently, it was suggested that metronomic chemotherapy exerts anti-angiogenic effects by inducing thrombospondin-1 (TSP-1) and early growth response-1 (EGR-1), and antitumor effects by su...
Recent advances in 3D printing are revolutionizing manufacturing, enabling the fabrication of structures with unprecedented complexity and functionality. Yet biological systems are able to fabricate systems with far greater complexity using a process that involves assembling and folding a linear string. Here, we demonstrate a 1D printing system that uses an approach inspired by the ribosome to ...
We determined the composition of ~30-m.y.-old solutions extracted from fluid inclusions in one of the world's largest and richest silver ore deposits at Fresnillo, Mexico. Silver concentrations average 14 ppm and have a maximum of 27 ppm. The highest silver, lead and zinc concentrations correlate with salinity, consistent with transport by chloro-complexes and confirming the importance of brine...
The tumor suppressor function of PTEN is strongly linked to its ability to dephosphorylate phosphatidylinositol-3,4,5 trisphosphate and, thereby, control cell growth, survival, and migration. However, the mechanism of action of PTEN in living cells is largely unexplored. Here we use single-molecule TIRF microscopy in living cells to reveal that the enzyme binds to the membrane for a few hundred...
این پژوهش با هدف بررسی تأثیر مالچ کاه و کلش بر روی توزیع رطوبت در نیمرخ خاک و شبیهسازی جریان آب در خاک تحت تأثیر آب زیرزمینی و شور، با استفاده از نرمافزار HYDRUS-1D انجام شد. بدین منظور، آزمایش لایسیمتری در دو خاک با بافتهای شنی و لوم با سه سطح مختلف شوری آب زیرزمینی شامل 5، 10 و 15 دسیزیمنس بر متر، با و بدون پوشش مالچ و در سه تکرار، در بازه زمانی 3 ماهه انجام شد. مقدار رطوبت بهوسیله دست...
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