In this position statement we discuss the state of the art and role of formal specification and modelling techniques in different periods with special focus on the work of the TFS-group at TU-Berlin. In the past (1970 – 1990) single formal specification techniques have been developed with little impact on practical software development. In the present (1990 – 2010) integrated and visual modelli...

The spatio-temporal distribution of influenza is linked to variations in meteorological factors, like temperature, absolute humidity, or the amount of rainfall. The aim of this study was to analyse the association between influenza activity, and meteorological variables in Spain, across five influenza seasons: 2010-2011 through to 2014-2015 using generalized linear negative binomial mixed model...

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Central Europe was characterized by a humid-temperate climate in the 20(th) century. Climate change projections suggest that climate in this area will shift towards warmer temperatures by the end of the 21(st) century, while projected precipitation changes are highly uncertain. Here we show that the 2015 summer rainfall was the lowest on record since 1901 in Central Europe, and that climate mod...

Hidradenitis Suppurativa (HS) is a chronic, inflammatory disease that requires complex, multidisciplinary approach. Disease awareness and management have significantly changed in recent years part by the advent of new biologic drugs approval 2015. It unclear how these changes affected healthcare utilization. This study aims to characterize adults children with HS utilized medical care before af...

[1] Bengio, Yoshua, Louradour, Jérôme, Collobert, Ronan, and Weston, Jason. Curriculum learning. In ICML , 2009. [2] Kumar, M Pawan, Packer, Benjamin, and Koller, Daphne. Self-paced learning for latent variable models. In NIPS , 2010. [3] Shrivastava, Abhinav, Gupta, Abhinav, and Girshick, Ross. Training regionbased object detectors with online hard example mining. In CVPR , 2016. [4] Avramova,...

Land use, land cover (LULC) change technique is essential for measuring ecological quality, environmental sustainability, and uncontrolled development at various spatiotemporal scales. To construct effective use management plans, the probable future scenario of LULC changes can be easily detected utilizing a simulation technique.This study monitors models land-use in Okomu National Park over tw...

INTRODUCTION In 2010, Alzheimer's Disease International presented estimates of the global cost of illness (COI) of dementia. Since then, new studies have been conducted, and the number of people with dementia has increased. Here, we present an update of the global cost estimates. METHODS This is a societal, prevalence-based global COI study. RESULTS The worldwide costs of dementia were esti...