نتایج جستجو برای: 24 cell
تعداد نتایج: 1972762 فیلتر نتایج به سال:
Introduction: Auger electron based radioimmunotherapy (RIT) using 111In-DOTA-trastuzumab (111In-DOTA-antiHer2) feasibility was studied in vitro on a HER2/neu positive cell line, SkBr3. Methods:111In-DOTA-antiHer2 was prepared according to the optimized conditions followed by quality control tests including radioch...
Background and purpose: Because of theirmultipotency and ease of purification, amplification and immunomodulatory properties Mesenchymal stem cells (MSC), are anideal stem cell source for cell therapies. This study was done to investigat the effect of Rat MSCs on the survival neutrophils. Materials and methods: MSCs was isolated from rat (6-8 weeks) femoral and tibial bone marrow and cultu...
Background: Endocrine compounds, such as Bisphenol A (BPA), stimulate or inhibit the activities of hormones, nuclear receptors in the central nervous system, liver and other organs. They may be disposed of in the environment inadverdently around industrial sites. The aim of this study was to evaluate the cytotoxic effects of BPA on human lymphocytes in culture at varying concentrations. Method...
Background Spondyloarthritis (SpA) is characterised by chronic debilitating axial and peripheral joint inflammation, often concomitant with inflammatory bowel disease (IBD)-like gut phenotypes. However, the contribution of extra-articular pathologies to SpA not well understood. The ZAP-70 W163C BALB/c (SKG) mouse model develop arthritis, spondylitis IBD-like ileitis commencing from 1 week after...
BACKGROUND The stromal cell derived factor (SDF)-1/chemokine receptor (CXCR)-4 signaling pathway plays a key role in lung cancer metastasis and is molecular target for therapy. In the present study we investigated whether interleukin (IL)-24 can inhibit the SDF-1/CXCR4 axis and suppress lung cancer cell migration and invasion in vitro. Further, the efficacy of IL-24 in combination with CXCR4 an...
Background and purpose: Cancer is one of the major health challenges in the world. The efficacy of current treatments is low but their side effects are high. Cold atmospheric plasma (CAP) is a new modality for cancer treatment. This study aimed to compare the cytotoxicity effect of CAP on the cell line models of common cancers and normal cells. Materials and methods: In this experimental study...
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