A mutation in the delta-sarcoglycan (SG) gene with absence of delta-SG protein in the heart has been identified in the BIO14.6 cardiomyopathic (CM) hamster, but how the defective gene leads to myocardial degeneration and dysfunction is unknown. We correlated left ventricular (LV) function with increased sarcolemmal membrane permeability and investigated the LV distribution of the dystrophin-dys...

Background: Because of the importance of thyroid function and its effect on different organs, such as the heart, this study was aimed to evaluate the effect of levothyroxine on cardiac function in children with subclinical hypothyroidism. Methods: This quasi-experimental study was performed on children aged 4-12 years old with diagnosis of subclinical hypothyroidism in Amirkola Children's Hosp...

There are several reasons why this book might be of interest to a TEX user. First, LTEX has a prominent place in the book. Second, the book describes a very interesting offshoot of literate programming, a topic traditionally popular in the TEX community. Third, since a number of TEX users work with data analysis and statistics, R could be a useful tool for them. Since some TUGboat readers are l...

326 ISSN 1436-4522 (online) and 1176-3647 (print). This article of the Journal of Educational Technology & Society is available under Creative Commons CC-BY-ND-NC 3.0 license (https://creativecommons.org/licenses/by-nc-nd/3.0/). For further queries, please contact Journal Editors at [email protected]. The Chicago Handbook of University Technology Transfer and Academic Entrepreneurship (Boo...

High-dose estrogen exposure during adolescence has been hypothesized to increase a woman's breast cancer risk, possibly mediated through an increase in mammographic density, a well-established breast cancer risk factor. In 2006 to 2007, we conducted a retrospective study of women assessed for tall stature as an adolescent between 1959 and 1993. Eligible participants were ages > or =40 years and...

Abstract Background There is growing recognition of metagenomic next-generation sequencing (mNGS) as a valuable diagnostic tool capable providing unbiased pathogen detection, but data on performance in low-resource settings remains scant. Here, we use mNGS nasopharyngeal (NP) swabs taken from subjects Cambodia to identify potential pathogens causing acute febrile illness. Methods Febrile aged 2...

Respiratory syncytial virus (RSV) infection can cause extensive airway inflammation, which is orchestrated by chemokines and their receptors. RSV-infected epithelial cells secrete many cytokines and chemokines, but little is known about regulation of chemokine receptors on target cells. We investigated the effects of conditioned media (CM) from RSV-infected epithelial cells on monocyte CCR1, CC...

powder with a melting point of about 50 °C is a lipid soluble vitamin like substance that inhabits inside of the inner mitochondrial membrane where it functions as an integral part of electron transport of oxidative phosphorylation. It is used as a nutritional supplement, antioxidant and in the treatment of cardiovascular disorders such as angina pectoris, hypertension, and congestive heart fai...