rheumatoid arthritis (ra) is a chronic autoimmune disease, which can lead to joint destruction and disability. pannus formation due to chronic synovitis is the hallmark of ra. oxidative stress as a consequence of immune cell activation and disease-modifying anti-rheumatic drugs can prevent inflammation and tissue destruction. silymarin, an antioxidant extract from silybum marianum, has been tra...

osteoporosis (op) is a frequent complication of rheumatoid arthritis (ra) and longitudinal studies have documented increased rate of bone loss in ra patients. to determine the frequency of low bone mass as well as the influence of disease duration and corticosteroid use on bone mass in patients with ra, 88 patients with ra and 112 age matched controls were studied. bone densitometry was perform...

background: osteoporosis (op) is a common complication of inflammatory arthritis such as rheumatoid arthritis (ra). in this study we evaluated osteoporosis and its related factors in ra patients. methods: this cross - sectional study was carried out from 2010 to 2011 on 121 women with ra aged 45-75 years. these patients were selected and divided in two groups according to their bone mineral den...

background: antiphospholipid antibody syndrome (aps) can either occur as a primary syndrome or associated with other autoimmune diseases such as systemic lupus erythematosus (sle). anticardiolipin antibody (acl) of igg and/or igm isotype in blood, measured by a standardized elisa is the most acceptable laboratory criteria. aps igg isotype, particularly igg2 subclass is more strongly associated ...

this cross-sectional study is conducted to determine the prevalence of asymptomatic cervical spine subluxation in rheumatoid arthritis patients by plain radiographs and its relation to demographic and clinical characteristics, disease activity measures and medications. 100 rheumatoid arthritis patients (18 male and 82 female) were selected randomly, according to the american college of rheumato...

background and aim: autoimmune inner ear disease (aied) may accompany certain systemic conditions, such as rheumatoid arth­ritis, and manifest audiovestibular dysfunction. this study aimed to compare the vestibular function between rheumatoid arthritis (ra) patients and normal subjects using cervical vestibular-evoked myogenic potentials and caloric tests. methods: in this cross-sectional study...

background and objectives: mycoplasma arthritidis mitogen (mam) superantigen has been shown to induce chronic arthritis, which resembles human rheumatoid arthritis (ra) in a rodent model. however, its role as a causative agent in human ra is not well understood yet. the aim of this study was to investigate the presence of mam superantigen gene in the synovial fluid (sf) of ra patients. material...

background: rheumatoid arthritis (ra) is an autoimmune systemic disease. most common autoimmune diseases are multisystem disorders that may also present with otological manifestations, and autoimmune inner ear disease accompanied by vestibular dysfunction. this study aimed to compare the vestibular function between ra patients and normal subjects using cervical vestibular evoked myogenic potent...