The DNA-dependent ATPase activity of the recA protein of Escherichia coli shows a complex dependence on ATP concentration. With a single-stranded (SS) DNA cofactor, the Hill coefficient for ATP is 3.3 at pH 8.1 and 1.4 at pH 6.2. With a double-stranded (DS) DNA cofactor, the Hill coefficient is 3.3 at pH 6.2 (no reaction is detectable at pH 8.1). In the presence of SS DNA, the Km for ATP is 20 ...

This paper suggests a macroscopic model describing the thermo-chemo-mechanical behaviour of ceramic dense membrane for oxygen separation application. This work takes in account to oxygen permeation and strain induced by stoichiometry variation with working conditions. This model, developed within the traditional framework of phenomenological approach, is based on the assumption of strain partit...

A central challenge in designing and administering effective anticoagulants is achieving the proper therapeutic window and dosage for each patient. The Hill coefficient, nH, which measures the steepness of a dose-response relationship, may be a useful gauge of this therapeutic window. We sought to measure the Hill coefficient of available anticoagulants to gain insight into their therapeutic wi...

We investigate a model of stratified economic interactions between agents when the notion of spatial location is introduced. The agents are placed on a network with near-neighbor connections. Interactions between neighbors can occur only if the difference in their wealth is less than a threshold value that defines the width of the economic classes. By employing concepts from spatiotemporal dyna...

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The recently suggested solar wind quasi-invariant [ QI ≡ (B/8π)/(ρv/2)] is a combination of magnetic field strength B, plasma density ρ and solar wind speed v. Measured in the solar wind near the Earth, the median value of QI was shown to be a reliable index of solar activity for the 28 year period holding a linear relation with sunspot numbers (SSN) with a high correlation coefficient (cc) of ...

in the present work, the modified nickel electrode was electrochemically fabricated and tested for the electro-oxidation of paracetamol in alkaline media. the methods of cyclic voltammetry (cv), chronoamperometry (ca), and impedance spectroscopy (eis) were used to determine kinetic parameters such as transfer coefficient (α), the catalytic reaction rate constants (k), and the diffusion coeffici...

The emergence and rapid spread of chloroquine resistant strains of Plasmodium falciparum has dramatically reduced the chemotherapeutic options. Towards this goal, the quantitative structure-activity relationship analysis of some synthesized 7-substituted 4aminoquinolines were performed for their antiplasmodial activity against chloroquine-resistant parasites to find out the structural features ...