Fraxin isolated from Acer tegmentosum is reported to exert potent anti-oxidative stress action. However, pharmacological activities of fraxin remain to be elucidated. This study investigated the potential hepatoprotective effects of fraxin and the underlying signaling mechanism involved. Treatment with fraxin significantly lowered the serum levels of aspartate aminotransferase (AST) and alanine...

background: aspartate transaminase (ast) is an important enzyme in parasite and liver tissue. the purpose of this investigation is to evaluate triclabendazole (tcbz) effect on ast activity of fasciola gigantica parasite. to compare of enzyme level of parasite and its host tissue, enzyme activity of f. gigantica parasite and liver tissues were also determined. method: the livers were collected f...

Guava leaves have been used to treat cough and pulmonary diseases; they have also served as anti inflammatory and haemostatic agent in china. This work is therefore aimed at investigating the effects of guava leaf extract on the liver enzymes of adult wistar rats. Twenty apparently healthy wistar rats were used for this study. They were allocated into four groups (A, B, C & D) of five animals e...

Submit Manuscript | http://medcraveonline.com MOJ Toxicol (2016), 2(1): 00026 Abbreviations: RPM: Revolutions Per Minute; AST: Serum Aspartate Aminotransferase; ALT: Serum Glutamate Pyruvate Transaminase; Scr: Serum Creatinine; BUN: Blood Urea Nitrogen; C: Control; V: Venom; VC : Vitamin; VVC: Venom+Vitamin C ; TBS :Tris Buffered Saline; SOD: Superoxide Dismutase; Cat: Catalase; GSH-Px: Glutath...

SUMMARY Three pa ticnts admitted because of slightly increased serum amino trans fcrases were found to have Addison's disease. A review of 16 other patients with addison 's disease who had serum aminotransferase activity (aspartate aminotrans­ferase (ASAT) and alanine aminotransferase (ALAT) J determined prior to treatment revealed one more patient with slightly increased aminotransferase acti...

The hepatoprotective activity of ethanolic extract of Wedelia calendulacea L. (Family: Asteraceae) 4 was studied against CCl induced, acute hepatotoxicity in rats. Hepatoprotective activity of the ethanolic-leaf extract of W.calendulacea (EEWC) was studied by estimating serum enzyme activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), prote...

The present study was conducted to evaluate the hepatoprotective activity of hydroalcoholic extract of Tabernaemontana divaricata Linn.against paracetamol induced liver damage in rats. The hydroalcoholic extract of Tabernamontana divaricata Linn. (600mg/kg) was administered orally to the animals with hepatotoxicity induced by paracetamol (3gm/kg). Silymarin (25mg/kg) was given as reference stan...

BACKGROUND: Cardiac Troponin I (cTnI) is known as a cardiac biomarker in determining the myocardial damage of diseases which affect the heart muscle. OBJECTIVES: This study aims to evaluate the serum cTnI concentration in Markhoz Breed goats suffering selenium (Se) deficiency and its correlation with electrocardiographic parameters, and activity of creatine kinase (CK) and aspartate aminotransf...

Acute liver damage caused by acetaminophen overdose is a significant clinical problem and could benefit from new therapeutic strategies. Objective. This study investigated the hepatoprotective effect of Thymus vulgaris essential oil (TEO), which is used popularly for various beneficial effects, such as its antiseptic, carminative, and antimicrobial effects. The hepatoprotective activity of TEO ...