OBJECTIVE To investigate whether sleep deprived people are perceived as less healthy, less attractive, and more tired than after a normal night's sleep. DESIGN Experimental study. SETTING Sleep laboratory in Stockholm, Sweden. PARTICIPANTS 23 healthy, sleep deprived adults (age 18-31) who were photographed and 65 untrained observers (age 18-61) who rated the photographs. INTERVENTION Pa...

background and objective : sleep deprivation (sd) is caused by a host of reasons and has numerous consequences on cardiac system. in this study, we aimed to assess the preconditioning effects of acute sd on ischemia (is)-induced ventricular arrhythmias in isolated rat hearts. materials and methods : male wistar rats randomly were placed into the four groups: is-group, acute sd group, control gr...

Effects of sleep deprivation and season on thermoregulation during 60 min. of leg-bathing (water temperature of 42 degrees C, air temperature of 30 degrees C, and relative humidity of 70%) were studied in eight men who completed all 4 experiments for normal sleep and sleep deprivation in summer and winter. Rectal temperature (T(re)), skin temperature, total body sweating rate (M(sw-t)), local s...

STUDY OBJECTIVES We recently proposed insufficient non-rapid eye movement sleep (NREMS) intensity to contribute to disturbed nocturnal sleep in patients with narcolepsy-cataplexy (NC). To test this hypothesis, we investigated the effect of physiologically intensified NREMS in recovery sleep following sleep deprivation. DESIGN Nocturnal baseline and recovery sleep architecture, and the sleep e...

Objective: Patients with chronic fatigue syndrome complain of unrefreshing sleep, and some have poor sleep indicative of sleep disruption. We hypothesized that some CFS patients had a disorder of arousal which interfered with normal sleep which would manifest itself by difficulty falling asleep after a night of sleep deprivation. To test this, we determined sleep latency after a night of sleep ...

This paper presents the history of research and the results of recent studies on the effects of sleep deprivation in animals and humans. Humans can bear several days of continuous sleeplessness, experiencing deterioration in wellbeing and effectiveness; however, also a shorter reduction in the sleep time may lead to deteriorated functioning. Sleeplessness accounts for impaired perception, diffi...

STUDY OBJECTIVES Sleep deprivation, time of day (circadian influences), and obstructive sleep apnea (OSA) all reduce performance and neurobehavioral function. We assessed the interactive effect of sleep deprivation and time of day on performance and neurobehavioral function in subjects with and without mild OSA. METHODS This was a cross-over study in which 13 subjects with mild OSA and 16 sub...

OBJECTIVES The thalamus and cerebral cortex are connected via topographically organized, reciprocal connections, which hold a key function in segregating internally and externally directed awareness information. Previous task-related studies have revealed altered activities of the thalamus after total sleep deprivation (TSD). However, it is still unclear how TSD impacts on the communication bet...

OBJECTIVES We sought to investigate the effects of sleep loss on high-sensitivity C-reactive protein (CRP) levels. BACKGROUND Concentrations of high-sensitivity CRP are predictive of future cardiovascular morbidity. In epidemiologic studies, short sleep duration and sleep complaints have also been associated with increased cardiovascular morbidity. Two studies were undertaken to examine the e...

The article by Gangwisch et al 1 in this issue of Hypertension identifies another significant health hazard associated with inadequate sleep. The authors document 2-fold greater risk for hypertension among adults in their fourth to sixth decades who sleep 5 hours each night. Whereas the independent risk of short sleep duration for developing hypertension is attenuated to 1.6-fold after adjustin...