*To whom all correspondence should be addressed. otal organic carbon (TOC) analysis is a fast and effective analytical technique for cleaning validation in pharmaceutical manufacturing. This nonspecific method can be used to test for residues of previously manufactured products, cleaning detergents, chemicals, solvents, by-products, degradants, and microbial contaminants. However, many factors ...

BACKGROUND Posaconazole is now widely used for prophylaxis of invasive fungal infections in immunocompromised patients. The pharmacokinetic properties of the drug argue for therapeutic monitoring, but so far described analytical methods have shortcomings with respect to application in a routine setting. The aim of our work was to develop an analytical method suitable for routine use. METHODS ...

In many countries, thiabendazole is used as a fungicide to prevent the decay of food and lengthen storage periods. However, in Korea, unauthorised does not have standards or specifications for use additive. this study, simple analytical method was developed validated using HPLC–PDA detect foods frequently consumed South Korea. The calibration curve obtained samples solid liquid containing banan...