Women in low- and middle-income countries (LMICs) have yet to benefit from recent advances in breast cancer diagnosis and treatment now experienced in high-income countries. Their unique sociocultural and health system circumstances warrant a different approach to breast cancer management than that applied to women in high-income countries. Here, we present experience from the last five years w...

There is a growing concern of low representation researchers from low-middle-income countries (LMICs) in the publication global health research high-impact peer-reviewed journals. Nobody denies that developing world generally face several obstacles to publishing their research. In this viewpoint, we share some barriers have observed our experience working both academia and practice middle-incom...

Summary Mental disorders (including substance use disorders, dementia, and self-harm) account for a substantial burden of disease economic costs in low-income middle-income countries (LMICs), yet they attract little funding. External resources are urgently needed but evidence on investments is scarce. This Health Policy paper uses 35 elite interviews documentary analyses to examine how...

Access to medications for chronic disease management is limited in many low and middle-income countries (LMICs), resulting in suboptimal care and avoidable morbidity and mortality. We performed a survey of COPD and asthma medicines that appeared on the national essential medicines lists (NEMLs) of 32 LMICs. Nearly all countries (>90%) had assigned essential medicines for treatment of exacerbati...

The Disease Control Priorities program (DCP) has pioneered the use of economic evidence in health. The theory of change (ToC) put forward by Norheim is a further welcome and necessary step towards translating DCP evidence into better priority setting in low- and middle-income countries (LMICs). We also agree that institutionalising evidence for informed priority-setting processes is crucial. Un...

Many health experts worry that the dra matic health gains of recent years may prove temporary if external resources wane. The U.S. Global Health Initiative (GHI) outlines an ambitious agenda to permanently strengthen the health systems of the countries we assist, but there is no consensus on how to do this. One promising approach applies the lessons learned from improving care in the U.S. healt...

Background The burden of non-communicable diseases (NCDs) in low- and middle-income countries (LMICs) is accelerating. Given that the capacity of health systems in LMICs is already strained by the weight of communicable diseases, these countries find themselves facing a double burden of disease. NCDs contribute significantly to morbidity and mortality, thereby playing a major role in the cycle ...

a major constraint to the application of any form of knowledge and principles is the awareness, understanding and acceptance of the knowledge and principles. systems thinking (st) is a way of understanding and thinking about the nature of  health systems and how to make and implement decisions within health systems to maximize desired and minimize undesired effects. a major constraint to applyi...

SUMMARY While initiatives exist to address the worldwide need for surgeons, none involve a student-driven solution from low- and middle-income countries (LMICs). In response to falling surgical residency enrolment in South Africa, the students at the University of Cape Town (UCT) founded the UCT Surgical Society and were subsequently instrumental in creating the International Association of Stu...

While other works have explained difficulties in applying ‘international’ guidelines in the field of regenerative medicine in so-called lowand middle-income countries (LMICs) in terms of ‘international hegemony’, ‘political and ethical governance’ and ‘cosmopolitisation’, this article on stem cell regulation in China emphasizes the particular complexities faced by large LMICs: the emergence of ...