practice and study of medicine in iran has a long and prolific history. iran has all characteristics of an indigenous culture which has so far discovered numerous natural products. unfortunately, scant research has been conducted on this system of medicine and ethnopharmacology of iran. gout is a historical disease that is still widespread all around the world. as numerous remedies used to be a...

the aim of the present study was to prepare and evaluate an osmotically controlled mucoadhesive cup-core (ocmc) containing aceclofenac. a special technique was used while preparing an ocmc. stability of ocmc was determined in natural human saliva, and it was found that both ph and device are stable in human saliva. ocmc was evaluated by weight uniformity, thickness, hardness, friability, swelli...

the ethanolic extract of wedelia chinensis (eewc) belonging to the family of asteraceae was evaluated by hot plate and acetic acid induced writhing methods to assess its analgesic activity. the extract was also evaluated for its by using on carrageenan, mediators such as histamine and serotonin induced paw oedema, and cotton pellet induced granuloma tests for its effect on acute and chronic pha...

Neuro-inflammation is the inflammation of nervous tissue due to oxidative stress, aging and autoimmunity and the major cause of Alzheimer's, Parkinson's and Huntington's disease. Periodontitis, the inflammation of the gums and supporting structures of the teeth, is a chronic peripheral immuno-inflammatory condition, affiliated with gram- negative, anaerobic bacteria that cause low-grade systemi...

Background and objectives: The species of Cymbopogon are generally used as anti-bacterial, anti-fungal, anti-malarial, and anti-spasmodic agents, as well as in cold treatment.Due to the presence of piperitone in Cymbopogon schoenanthus, we were prompted to evaluate were prompted to assess the anti-nociceptive and anti-inflammatory properties of its essential O...

objective: solenostemon monostachyus is used in traditional medicine for the treatment of various ailments such as ulcer, hypertension, pains and inflammatory diseases. evaluation of anti-inflammatory and analgesic activities of s. monostachyus aerial parts was carried out to ascertain its uses in traditional medicine. materials and methods: the aerial parts of s. monostachyus was cold extracte...

Objective: Triptolide, the active component of Tripterygium wilfordii Hook F has been used to treat autoimmune and inflammatory conditions for over two hundred years in traditional Chinese medicine. However, the processes through which triptolide exerts immunosuppression and anti-inflammation are not understood well. In this review, we discuss the autoimmune disorders and inflammatory condition...

The aqueous leaves extract of Ocimum gratissimum was investigated for anti-nociceptive and anti-inflammatory effects in mice and rats. The models used to study the effect on nociception are the acetic acid-induced abdominal constriction test, hot-plate method in mice. The anti-inflammatory effect was investigated employing the formalin-induced hind-paw oedema in rats. The extract caused a signi...

Fruits of Olea europaea L. have been used for centuries in folk medicine to treat many inflammatory diseases. In order to evaluate the anti-nociceptive activities of the methanolic and aqueous extracts of defatted fruits of O. europaea, formalin test was used and for evaluation of anti-inflammatory effects of the extract, the volume of paw edema was measured. The results revealed that both extr...

Background and objectives: Otostegia persica (Labiatae) is an endemic plant of Iran and is used for its anti-inflammatory properties in folk medicine of Sistan and Baluchestan province. The aim of the present study was to investigate the anti-nociceptive and anti-inflammatory effects of O. Persica different fractions and identification of the natural compounds...