Background and Aims: Acinetobacter baumannii (A. baumannii) is an important multidrug-resistant opportunistic pathogen frequently causing various nosocomial infections and is a serious threat to burn patients. These infections are usually caused by the outbreak strains. The aim of this study was to show antibiotic resistance pattern and molecular typing of A. baumannii genes isolates collected ...

The potential coverage of antibiotic-resistant pneumococci causing acute otitis media (AOM) by 7-, 9-, and 11-valent conjugate pneumococcal vaccines was studied in southern Israel. A total of 876 cases of pneumococcal AOM were studied in the context of various clinical conditions. Of the isolates, 68% were resistant to >/=1 drug, 61% were resistant to penicillin, and 13% were resistant to >/=3 ...

Enterococci have emerged as significant nosocomial pathogens. Enterococci with resistance to commonly used antibiotics are appearing more frequently. We encountered at our institution several infections caused by Enterococcus faecium with high-level resistance to ampicillin, vancomycin, and gentamicin. The optimal antibiotic therapy for serious infections with unusually resistant enterococci ha...

Antibiotics are the 'wonder drugs' to combat microbes. For decades, multiple varieties of antibiotics have not only been used for therapeutic purposes but practiced prophylactically across other industries such as agriculture and animal husbandry. Uncertainty has arisen, as microbes have become resistant to common antibiotics while the host remains unaware that antibiotic resistance has emerged...

Little is known about the significance of insects as environmental reservoirs of antibiotic-resistant bacteria. We characterized the antibiotic resistome of the microbial community in gypsy moth larval midguts by applying functional metagenomics to cultured isolates. The minimum inhibitory concentrations of 12 antibiotics were determined for 44 cultured isolates, and antibiotic resistance genes...

The effects of the everninomicin antibiotic evernimicin (SCH27899) on growing Staphylococcus aureus cells were investigated. Cellular growth rates and viable cell numbers decreased with increasing antibiotic concentrations. The rate of protein synthesis, measured as (35)S-amino acid incorporation, declined in parallel with the growth rate. Significantly, the formation of the 50S ribosomal subun...

Antimicrobial-resistant bacteria are an emerging problem globally and are associated with increased patient morbidity and mortality. Within hospitals, antibiotic resistant bacteria continue to increase in incidence. As evidenced by the Centers for Disease Control and Prevention National Healthcare Safety Network collection of data across a large number of hospitals, resistance rates for vancomy...

As researchers become increasingly concerned about measuring and preserving biodiversity, microbiologist Hugh Pennington, at the University of Aberdeen, recently wrote that where you stand on biodiversity depends on where you sit. As a researcher working with some of the novel antibiotic-resistant bacteria, Pennington wrote of his lifelong efforts to fight biodiversity and to research all means...

Abstract Background Based on the analysis of infections and antibiotic usage in years 2013 2014, an evidence-based protocol was developed implemented our cardiac surgical intensive care unit (CSICU). This study intends to impact this new sensitivity profiles common gram-negative bacteria CSICU. Methods The medical records patients who underwent surgery at center, between January 2017 December 2...