Achillea fragrantissima Forssk. (Family: Asteraceae) has been used as a natural remedy in the Arabian region for its antihyperglycemic activity. As result of intensive demand this plant folk medicinal uses, scarcity become problematic. This study explored methods that produce an efficient vitro culture protocol conservation well enhancement hypoglycemic A. cultures on Murashige and Skoog (MS) m...

Background: Plant oxysterols like 28-homobrassinolide (HB) exhibit partial structural homology to oxycholesterols. HB’s effect in cell metabolism was therefore investigated using rat model. Results: Oral administration of HB to streptozotocin induced diabetic male albino wistar rats, reduced circulating glucose level to normal level. Serum insulin content was increased by HB treatment. HB eleva...

The anti-diabetic activity of ethanolic extract of Holarrhena antidysenterica leaves (EEHA) was evaluated against alloxan (100 mg/kg, i.p.) and streptozotocin (STZ) (50 mg/kg, i.p.) induced diabetes in Wistar rats. Oral glucose tolerance test was also performed. The effect was compared with antidiabetic activity of glibenclamide (5 mg/kg, p.o.). In alloxan and STZ induced hyperglycemic rats, a ...