Widespread overuse and inappropriate use of antimicrobial drugs continues to fuel an increase in antimicrobial resistance and leads to consequent treatment complications and increased healthcare costs. In the present study we aimed to describe antimicrobial drug consumption and predictors and to identify potential targets for antimicrobial stewardship. This was a prospective observational study...

plants are potent biochemists; biologically active compounds present in the medicinal plants have always been ofgreat interest to scientists working in this field. thus, the aim of the current study was to screen the antimicrobial activity of acacia nilotica, ziziphus mauritiana, bauhinia variegate and lantana camara against some selected clinical isolated strains. although previous studies hav...

surgical site infections are one of the most important post-surgery complications. antimicrobial prophylaxis has been used routinely in surgeries to reduce infection incidence. however, inappropriate selection of antimicrobial agents or dosing can develop antimicrobial resistance, serious adverse reactions and prolong hospitalization. current study aimed to examine prophylactic antibiotic presc...

Consumer demand for affordable fish drives the ever-growing global aquaculture industry. The intensification and expansion of culture conditions in the production of several finfish species has been coupled with an increase in bacterial fish disease and the need for treatment with antimicrobials. Understanding the molecular mechanisms of antimicrobial resistance prevalent in aquaculture environ...

results ll-37 and its truncated analogs were effective in inhibiting the growth of pdrab and had a rapid killing ability. after exposure to the peptides, the development of the pdrab biofilm was inhibited. strong inhibitory and dispersion effects of ff/cap18 on the biofilm were confirmed by fluorescence microscopy and field emission scanning electron microscopy. conclusions this results show th...

antimicrobial resistance in pathogens not only in hospitals but also in the community has become an important public health problem. the aim of this study was to determine the antimicrobial resistance patterns of predominant pathogens from hospitalized and outpatients in a university hospital in tehran, iran. a total of 820 samples of common gram-negative and gram-positive bacteria were collect...

conclusions the results showed that e. coli isolated from patients with uti had eight virulence factors with high frequencies. moreover, these results alleged a direct connection between virulence factors and antimicrobial resistance in e. coli. results the frequency of virulence factors papc, afa, sfa/foc, fimh, hly, neuc, ibea, and iucc were 53.3%, 51.7%, 53.3%, 56.7%, 23.3%, 31.7%, 20%, and ...

Spices like turmeric, ginger, alliums are indispensable for the preparation of our daily food and are reported to possess compounds, which have varied beneficial biological effects and also prevent the microbial spoilage of food. This study evaluates the antioxidant and antimicrobial activity of spice extracts such as ginger, turmeric and garlic by 2, 2’-Diphenyl-1-picrylhydrazyl (DPPH) Radical...