auto-inflammatory syndromes are a new group of distinct hereditable disorders characterized by episodes of seemingly unprovoked inflammation (most commonly in skin, joints, gut, and eye), the absence of a high titer of auto-antibodies or auto-reactive t cells, and an inborn error of innate immunity. a narrative literature review was carried out of studies related to auto-inflammatory syndromes ...

Di erent signal realizations generated from a given source may not appear the same. Time shifts, frequency shifts, and scales are among the signal variations commonly encountered. Time-frequency distributions (TFDs) covariant to time and frequency shifts and scale changes re ect these variations in a predictable manner. Based on such TFDs, representations invariant to these signal distortions a...

The implementation of automation in the multistep flow synthesis is essential for transforming laboratory-scale chemistry into a reliable industrial process. In this review, we briefly introduce the role of automation based on its application in synthesis viz. auto sampling and inline monitoring, optimization and process control. Subsequently, we have critically reviewed a few multistep flow sy...

All tumor cell lines that have been tested are defective for Myc auto-repression, and have high levels of Myc produced from wild type loci and re-arranged loci. Like mammalian Myc auto-repression, Myc protein represses the expression of its gene, dmyc, in Drosophila. This activity requires Polycomb (Pc), since RNAi for Pc in the embryo eliminates Myc auto-repression. We have observed that upon ...

An international strategic alliance is a difficult partnership, often creating complicated issues relating to technical decisions, management, and various cultural matters. The purpose of this research is to consider the condition of a successful international strategic alliance based on the experience of a Japan-U.S. company. The auto industry is currently experiencing a period of major change...

Ignition and propagation of a reaction front in a counterflow system of an iso-octane/air stream mixing with an exhaust gas stream is computationally investigated to understand the fundamental characteristics of homogeneous charge compression ignition (HCCI) auto-ignition. Various mixing rates are imposed on the system and the effects of dissipation rates on auto-ignition are studied. Ignition ...

The ability of the human visual processing system to accommodate and retain clear understanding or identification of patterns irrespective of their orientations is quite remarkable. Conversely, pattern invariance, a common problem in intelligent recognition systems is not one that can be overemphasized; obviously, one‘s definition of an intelligent system broadens considering the large variabil...

INTRODUCTION Essential tremor (ET) shows amplitude fluctuations throughout the day, presenting challenges in both clinical and treatment monitoring. Tremor severity is currently evaluated by validated rating scales, which only provide a timely and subjective assessment during a clinical visit. Motor sensors have shown favorable performances in quantifying tremor objectively. METHODS A new hig...

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