Biomechanical Signaling Physarum polycephalum, a slime mold with one cell and no brain, is remarkable new model for understanding basal cognition. Its living material deforms its own structure to interact the objects around it. In article number 2008161, Michael Levin co-workers show that senses strain in substrate, using biomechanical signaling assess environment express preferences as directi...

Ischemic tracheal complications due to the ETT cuff occur in approximately 10 percent of mechanically ventilated critically ill patients despite the use of high-volume, low-pressure ETT cuffs. Using a laboratory model, we studied the effects of airway pressure on three different ETT cuff designs, including two "low pressure" designs. Positive airway pressure acted on the "low pressure" cuffs to...

BACKGROUND/AIMS The Compliance Questionnaire-Rheumatology (CQR) is a validated scale to evaluate patient compliance for anti-rheumatic medications. We developed a Korean version of the CQR (KCQR) and confirmed its reliability and validity. METHODS We prepared the KCQR by translating and back-translating the original CQR with modifications to adapt it to Korean culture. Fifty Korean patients w...

Effect of posture on the hypercapnic ventilatory response was studied on the anaesthetized rats by using rebreathing techniques in the supine and head-down positions. There were no statistically significant alterations in tidal volume, frequency, minute ventilation, and P(ET)CO(2)between the head-down and supine positions during breathing at rest. However, the esophageal pressure inspiratory sw...

Ventilator settings resulting in decreased driving pressure (ΔP) are positively associated with survival. How to further foster the potential beneficial mediator effect of a reduced ΔP? One possibility is promoting the active modification of the lung's "mechanical scenario" by means of lung recruitment and positive end-expiratory pressure selection. By taking into account the individual distrib...

OBJECTIVE To describe and apply a semi-quantitative MRI scoring system for multi-feature analysis of cartilage defect repair in the knee by osteochondral allografts, and to correlate this scoring system with histopathologic, micro-computed tomography (μCT), and biomechanical reference standards using a goat repair model. DESIGN Fourteen adult goats had two osteochondral allografts implanted i...

OBJECTIVE To evaluate if chronic low back pain patients perform manual material handling tasks differently from control subjects. DESIGN Comparative study using a repeated measures design. BACKGROUND No study evaluated the lifting technique of back pain patients relative to control subjects during free style lifting and lowering tasks. Previous findings suggest that lowering would be more h...

In recent years several different methods have been developed to assess mechanical exposures, which are related to musculoskeletal disorders in ergonomic epidemiology. Each of these methods is capable of measuring one or more aspects of risk factors, but has drawbacks as well. Improper application of methods might result in biased exposure estimates, which has serious consequences for risk esti...