Last Updated: July 28, 2009 Importance Brucella infections have recently been recognized in seals, sea lions, walruses, dolphins, porpoises, whales and an otter. This organism appears to be widespread in marine mammals, and has probably been endemic in these populations for a long time. The clinical significance is uncertain. A few infections have been associated with placentitis/abortions, neo...

Brucellosis is named after Dr. David Bruce who first isolated the bacterium that caused Malta fever from four fatal cases amongst the British forces on the island. The genus Brucella was subsequently proposed after similar bacteria were isolated from cattle and swine and the zoonotic connection recognized. The close similarities between these isolates were acknowledged but nomen species were su...

Brucellosis remains an important anthropozoonosis worldwide. Brucella species are genetically homogeneous, and thus, the typing of Brucella species for epidemiological purposes by conventional molecular typing methods has remained elusive. Although many methods could segregate isolates into the phylogenetically recognized taxa, limited within-species genetic diversity has been identified. Recen...

Brucella is an intracellular bacterium that causes chronic brucellosis in humans and various mammals. The identification of host-Brucella interaction is crucial to understand host immunity against Brucella infection and Brucella pathogenesis against host immune responses. Most of the information about the inter-species interactions between host and Brucella genes is only available in the text o...

Brucella infections have recently been recognized in seals, sea lions, walruses, dolphins, porpoises, whales and an otter. This organism appears to be widespread in marine mammals, and has probably been endemic in these populations for a long time. The clinical significance is uncertain. A few infections have been associated with placentitis/abortions, neonatal mortality, meningoencephalitis, a...

Rapid and precise diagnosis in natural field cases of bovine abortion caused by Brucella abortus warrants the use of the most sensitive and reliable diagnostic methods. In the present study, bacterial isolation, serology, gross, histopathology, immunohistochemistry and polymerase chain reaction technique(s) were applied. Sero-prevalence studies showed the rate of 28.86% positive cases using the...

Brucella infections have recently been recognized in seals, sea lions, walruses, dolphins, porpoises, whales and an otter. This organism appears to be widespread in marine mammals, and has probably been endemic in these populations for a long time. The clinical significance is uncertain. A few infections have been associated with placentitis/abortions, neonatal mortality, meningoencephalitis, a...

Filter paper discs impregnated with solutions containing 0.25, 0.5 and 1 mg/milliliter of thionin acetate, 0.75 and 1.5 mg/milliliter of basic fuchsin and 0.5 mg/milliliter of thionin blue were used in the typing of Brucella species. All the strains used reacted as expected, proving this new technique to be reliable in the identification of Brucella species. The method is less expensive and the...

BACKGROUND Brucella spp. are Gram-negative, facultative intracellular bacteria that cause brucellosis, one of the commonest zoonotic diseases found worldwide in humans and a variety of animal species. While several animal vaccines are available, there is no effective and safe vaccine for prevention of brucellosis in humans. VIOLIN (http://www.violinet.org) is a web-based vaccine database and an...

INTRODUCTION Brucellosis in Egypt is an endemic disease among animals and humans. In endemic developing countries, dairy products produced from untreated milk are a potential threat to public health. The aim of this study was to detect brucellae in milk and milk products produced from apparently healthy animals to estimate the prevalence of contamination. METHODOLOGY Two hundred and fifteen u...