AIM Though odontogenic lesions have in common origin from the primitive odontogenic epithelium , there is a diversity in their initiation behavior and growth. The aggressive nature of odontogenic keratocyst similar to ameloblastoma in comparision with the other common odontogenic (dentigerous and radicular) cyst could be due to possible differences in their epithelial linings. PCNA (Proliferati...

p53 and PCNA expression in keratocystic odontogenic tumors compared with selected odontogenic cysts Summary: The aim of this study was to evaluate p53 and PCNA expression in different odontogenic lesions regarding their different clinical behaviors. Slices prepared from 94 paraffin-embedded tissue blocks (25 radicular cysts (RC), 23 dentigerous cysts (DC), 23 keratocystic odontogenic tumors (KC...

introduction calcifying odontogenic cyst (coc) is a unique and uncommon odontogenic cyst classified into four groups of cystic, odontoma producing, ameloblastomatous proliferating and neoplastic ones. case presentation a 34-year-old iranian man complaining of a painless facial and palatal swelling of the left side of the maxilla persisted for approximately three years was referred to the depart...

Peripheral Calcifying Odontogenic Cyst (PCOC) is the extraosseous form of calcifying odontogenic cyst that limited to peripheral soft tissue without bony involvement. This case report presents a PCOC manifested as progressive growth gingival mass in young male treated with excisional biopsy. Histological examination confirmed diagnosis presence characteristic ghost cells and sporadic calcificat...

Calcifying cystic odontogenic tumor (CCOT) previously known as calcifying odontogenic cyst (COC) is a relatively rare lesion. It was first reported as a separate pathologic entity by Gorlin et al in 1962 as a likely analog of the cutaneous calcifying epithelioma of Malherbe or pilomatricoma. Because of the diverse clinicohistologic features and the various neoplastic potential, there have been ...

Calcifying odontogenic cyst (COC) is an uncommon benign cystic neoplasm of odontogenic origin, which shows extensive diversity in its clinico-pathological appearances and biological behavior. It most commonly occurs in broader age group of 1-82 years in anterior part of jaws which is classically described by presence of ghost cells. There are variants of COC according to clinical, histopatholog...

A male patient presented with an extraordinarily large calcifying epithelial odontogenic tumor (CEOT or Pindborg-tumor) that affected the maxilla. The disease became evident due to alterations in the facial aspect, in particular of the perioral region, caused by the expanding tumor. CEOT is characterised by the slowly growing mass of part of the jaws. Multilocular or extraosseous manifestations...

En la ortopantomografía (fig. 1) se observaba en el maxilar izquierdo la existencia de una lesión expansiva de densidad heterogénea con calcificaciones en su interior. En la TC del maxilar superior (fig. 2A y B) se confirmó la tumoración de aspecto quístico en el maxilar superior izquierdo, centrada a nivel molar en la arcada dentaria. Se evidenciaba que la tumoración hacía relieve en el seno m...

AIM To reevaluate all cases previously diagnosed as calcifying odontogenic cyst (COC) from the archives of the Department of Oral Pathology at Mashhad Faculty of Dentistry from 1978 to 2008. MATERIALS AND METHODS Clinical histories and microscopic slides of all cases diagnosed as COC were reviewed and analyzed statistically. The information about patients such as age, sex, clinical features, ...